Column: History of Chromatography - Chromatography Online
Column: History of Chromatography
With each installment of this column, a different industry veteran covers an aspect of the evolution and continued development of the science of chromatography, from its birth to its eventual growth into the high-powered industry we see today.

Professor Barry L. Karger: Scientist, Mentor, and Innovator

July 1, 2014

A review of Professor Barry L. Karger's years as a teacher and mentor, as well as his many scientific accomplishments

Joseph Jack Kirkland: HPLC Particle Pioneer

May 1, 2014

An interview with Jack Kirkland on his pioneering career in HPLC

The Early Development of Size-Exclusion Chromatography: A Historical Perspective

July 1, 2013

This column installment traces the early development of SEC from its inception to its acceptance as a modern analytical technique.

Man of the Masses

February 1, 2013

An interview with Fred McLafferty, professor emeritus at Cornell University, about his pioneering career in mass spectrometry

Phyllis Brown: A Pioneer in HPLC

October 23, 2012

Karyn M. Usher of West Chester University of Pennsylvania interviews Phyllis R. Brown, professor emerita of the University of Rhode Island, about her distinguished career in chromatography.

50 Years in Chromatography and Sorption Techniques: A Look from the East

July 1, 2012

In both East and West, new ideas have often met resistance.

Efficient HPLC Method Development and Personal Reflections

April 1, 2012

A pioneer in high performance liquid chromatography reflects on his career and how "enlightened trial-and-error" can reduce the effort involved in method development.

Icons of Chromatography: Harold McNair

February 1, 2012

An interview with Harold McNair reveals his greatest accomplishments and proudest moments.

The Evolution of Chiral Chromatography

December 1, 2011

The development and application of chiral chromatography is described.

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LCGC COLUMNISTS 2014

Column Watch: Ron Majors, established authority on new column technologies, keeps readers up-to-date with new sample preparation trends in all branches of chromatography and reviews developments. LATEST: When Bad Things Happen to Good Food: Applications of HPLC to Detect Food Adulteration


Perspectives in Modern HPLC: Michael W. Dong is a senior scientist in Small Molecule Drug Discovery at Genentech in South San Francisco, California. He is responsible for new technologies, automation, and supporting late-stage research projects in small molecule analytical chemistry and QC of small molecule pharmaceutical sciences. LATEST: HPLC for Characterization and Quality Control of Therapeutic Monoclonal Antibodies


MS — The Practical Art: Kate Yu brings her expertise in the field of mass spectrometry and hyphenated techniques to the pages of LCGC. In this column she examines the mass spectrometric side of coupled liquid and gas-phase systems. Troubleshooting-style articles provide readers with invaluable advice for getting the most from their mass spectrometers. LATEST: Radical Mass Spectrometry as a New Frontier for Bioanalysis


LC Troubleshooting: LC Troubleshooting sets about making HPLC methods easier to master. By covering the basics of liquid chromatography separations and instrumentation, John Dolan is able to highlight common problems and provide remedies for them. LATEST: How Much Can I Inject? Part I: Injecting in Mobile Phase


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