September 6, 2012
By:
René Borstel
Sample clean-up using solid-phase extraction (SPE) and similar methods can sometimes be both time-consuming and expensive. The purification of complex plant extracts requires special care in particular. A robust and sensitive online SPE sample preparation method is described for the determination of steviol glycosides.
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August 2, 2012
By:
J. Heroult, T. Havard, H. Goenaga Infante
This work demonstrates the potential of the simultaneous on-line hyphenation of asymmetric flow field flow fractionation (AF4) to inductively coupled plasma-mass spectrometry (ICP-MS) and ultra violet-visible/multi angle light scattering (UV-vis/MALS) detection as a promising and simple tool to obtain information on the multi-element speciation and absolute molecular mass of human plasma proteins such as albumin and transferrin: the two main proteins that have been proposed to bind and transport metal ions in this biological fluid.
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July 4, 2012
By:
Martin Giera
The Column spoke to Martin Giera of Leiden University Medical Centre, Leiden, The Netherlands, about developments in biomarker discovery.
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July 2, 2012
Wyatt Application Note
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July 2, 2012
Biotage Application Note
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July 2, 2012
Wyatt Application Note
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May 1, 2012
By:
Andras Guttman
LC–MS and CE–MS are the go-to techniques for characterizing biologics, but often help is needed from a range of other methods.
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