Application Notes: LC/HPLC

Aug 21, 2017
Sponsored Content - NA
Typically, silica-based size-exclusion columns require high concentrations of non-volatile salts to facilitate timely elution, and require dedicated columns for GPC or GFC applications. Addressing these issues, our new size exclusion chromatography silica-based column utilizes volatile salts making it compatible with MSn, CAD or ELSD; provides excellent results in aqueous and/or organic mobile phases; and offers the mechanical stability of silica-based columns.
Aug 21, 2017
Sponsored Content - NA
Decrease analysis time for fluorochemicals with no sacrifice in chromatographic performance.
Aug 21, 2017
Sponsored Content - EU
Decrease analysis time for fluorochemicals with no sacrifice in chromatographic performance.
Aug 17, 2017
Sponsored Content - NA
Polar compounds, including those with biological interest, can be very hard to analyze by reversed-phase or HILIC HPLC or LC–MS. This application note shows how some sugars, sugar alcohols, and amino acids are readily and precisely retained by ANP HPLC using Cogent silica hydride columns.
Aug 17, 2017
Sponsored Content - NA
This application note shows a one-step analysis of a 20-mer DNA-based oligonucleotide, using a TSKgel SuperQ-5PW column. The effect of pH, temperature, and sample load on the selectivity and resolution, particularly in reference to the separation of N-1 and N+1 peaks from the main peak, are discussed. The aligned selectivity of this anion exchange column with its process scale counterparts makes the TSKgel SuperQ-5PW column extremely useful for the separation of oligonucleotides.
Aug 16, 2017
Sponsored Content - NA
Proteins and peptides are analytes of increasing interest within the pharmaceutical industry. While retention modelling has been successfully used for optimization of analytical scale separations of small molecules for approximately 30 years, it has not been expanded to accurate modelling of protein separations.
Aug 10, 2017
Sponsored Content - NA
Synthetic cannabinoids (Spice) are a family of compounds that when consumed mimic the effects of marijuana. These products are often marketed as “legal alternatives to cannabis” or “legal highs” and have dramatically increased in popularity among different drug user populations.
Aug 07, 2017
Sponsored Content - EU
Synthetic cannabinoids (Spice) are a family of compounds that when consumed mimic the effects of marijuana. These products are often marketed as “legal alternatives to cannabis” or “legal highs” and have dramatically increased in popularity among different drug user populations. By paring UCT’s Styre Screen® HLD polymeric solid phase extraction column with the Selectra® DA HPLC column, one can not only target current metabolites of interest, but also the new ones being synthesized in order to keep up with the constantly changing market.
Aug 01, 2017
Sponsored Content - EU
This application note describes a combined approach of analytical method development and method transfer by direct emulation of different target HPLC systems.
Aug 01, 2017
Sponsored Content - NA
This application note describes a combined approach of analytical method development and method transfer by direct emulation of different target HPLC systems.
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