Application Notes: LC/HPLC

Aug 16, 2017
Sponsored Content - NA
Proteins and peptides are analytes of increasing interest within the pharmaceutical industry. While retention modelling has been successfully used for optimization of analytical scale separations of small molecules for approximately 30 years, it has not been expanded to accurate modelling of protein separations.
Aug 10, 2017
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Synthetic cannabinoids (Spice) are a family of compounds that when consumed mimic the effects of marijuana. These products are often marketed as “legal alternatives to cannabis” or “legal highs” and have dramatically increased in popularity among different drug user populations.
Aug 07, 2017
Sponsored Content - EU
Synthetic cannabinoids (Spice) are a family of compounds that when consumed mimic the effects of marijuana. These products are often marketed as “legal alternatives to cannabis” or “legal highs” and have dramatically increased in popularity among different drug user populations. By paring UCT’s Styre Screen® HLD polymeric solid phase extraction column with the Selectra® DA HPLC column, one can not only target current metabolites of interest, but also the new ones being synthesized in order to keep up with the constantly changing market.
Aug 01, 2017
Sponsored Content - EU
This application note describes a combined approach of analytical method development and method transfer by direct emulation of different target HPLC systems.
Aug 01, 2017
Sponsored Content - NA
This application note describes a combined approach of analytical method development and method transfer by direct emulation of different target HPLC systems.
Jul 24, 2017
Sponsored Content - EU
Antibiotics are widely used in veterinary medicine for treatment and prevention of disease and as growth promoters. Excessive usage of antibiotics might result in residue violations in animal originated food such as milk, meat, and others, and this can pose a risk to the health of humans. In this application note, we present a fast and sensitive LC–MS/MS method for the quantitative and confirmatory analysis of multiclass antibiotics in milk.
Jul 19, 2017
Sponsored Content - EU
Simultaneous immunosuppressant drugs tacrolimus, sirolimus, and cyclosporine A in serum are analyzed with a sensitive, fast, and accurate LC–MS/MS quantitation method. Utilizing a QSight™ 110 Triple Quadrupole Mass Spectrometer and using everolimus as an internal standard. Immunosuppressant drugs are used in allogeneic organ transplant patients to reduce the activity of the patient's immune system and lower the risk of organ rejection.
Jul 18, 2017
Sponsored Content - EU
A latest approach in bioethanol generation is the application of yeast and bacteria, which use C5 sugars for fermentation and the valorization of biorefinery byproducts. Here it is shown that a hemicellulose-like fermentation mash has a high content of the artificial sweetener xylitol and that its purification by HPLC can be accomplished using polymer-based Eurokat columns. The product is soluble in water and can easily be used for further applications.
Jul 17, 2017
Sponsored Content - NA
Shodex has developed a method for detecting the twenty essential amino acids using a single method on the HILICpak VC-50 2D under positive MS mode.
Jul 11, 2017
Sponsored Content - EU
This application note shows the seamless transfer of a method for the analysis of beta-blockers from an Agilent 1260 Infinity LC to an Agilent 1260 Infinity II LC.
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