Application Notes: LC
Enhanced separation of plasmid isoforms via HIC
Discover the outstanding separation of three plasmid DNA isoforms, linear, open circular and supercoiled in HIC mode using YMC’s BioPro HIC BF column.
Understanding the importance of pump performance
Real time monitoring of flow using a non-invasive flowmeter offers a new diagnostic tool for measuring performance & troubleshooting problems with pumps serving HPLC systems
Full-empty analysis of AAVs
This innovative AEX method replaces toxic TMAC with non-toxic choline-Cl, ensuring safety and efficiency in AAV capsid analysis, applicable across multiple AAV serotypes.
Benefits of UHPLC
This application note shows the performance of the KNAUER AZURA UHPLC system to speed up your method and increase throughput preserving resolution.
Realtime Monitoring of HPLC Pump Performance
The described method of continuous flow rate monitoring provides real-time validation of total HPLC system performance and as such can improve reliability of results.
Efficient Method Development of Oligonucleotides
This article describes how to achieve optimal separation of oligonucleotides and related impurities via a dedicated method development software package.
Chiral Columns for Oligonucleotides Analysis (Nov 2023)
Accurate purity assessment of oligonucleotide mixtures can be challenging due to their complexity. Daicel offers several solutions that provide unique selectivity.
Determination of Adenine and Guanine Nucleotides
The measurement of adenosine nucleotides represents important diagnostic measures concerning metabolic standing for the determination of various pathological states.
Separation of Fat-Soluble Vitamin K Congeners
The coagulation benefits of vitamin K1 are well known, however, the other congeners of the vitamin series are not as common (K2, K3, and K4), but equally contribute to a healthy disposition.
Poisoned by Plastic: Analysis of BPA (Nov 2023)
Plasticizers added to water bottles to add stability to the bottles can be unknowingly extracted in drinks leading to possible endocrine interactions.