Application Notes: LC/HPLC

Oct 01, 2017
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Chiral derivatives of xanthones have been reported to exhibit antitumor, antiepileptic, and anticonvulsant properties, among others, and often the reported biological activity depends on their stereochemistry. This application note features the use of the (S,S) Whelk-O 1 CSP for the enantioseparation of this important class of bioactive compounds.
Oct 01, 2017
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With all of the covalently bonded CSPs available in the market, the choice of solvents has increased. This note provides a study of various solvents tested on bonded and coated phases with separation, resolution, and the ability to scale up in mind.
Sep 27, 2017
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Various types of phosphorylated saccharides are involved with glycolysis, glyconeogenesis, glycometabolism, and other naturally occurring biological phenomena. One example of a phosphorylated saccharide includes fructose-2,6-bisphosphate the most powerful activator of phosphofructokinase. Recent research has shown the phosphorylated saccharide intermediates created during glyconeogenesis and glycometabolism can be used in other ways than naturally intended for a number of applications, drastically broadening the interest in phosphorylated saccharide.
Sep 26, 2017
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Read how mass detection delivers certainty and efficiencies to QC labs through this comprehensive pack of application notes, with examples from pharma, food, environmental, and chemical industries.
Sep 26, 2017
Sponsored Content - EU
Read how mass detection delivers certainty and efficiencies to QC labs through this comprehensive pack of application notes, with examples from pharma, food, environmental, and chemical industries.
Sep 25, 2017
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In this whitepaper, Mott PerfectPeak® Static Mixers are shown to achieve improved performance but with smaller internal volumes and lower back pressures. This provides increased sensitivity through better signal to noise ratios and lower limits of quantitation with improved peak shape, efficiency, and resolution even for difficult to mix gradients employing TFA as an additive.
Sep 25, 2017
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This paper illustrates “best practices” use of TLC prior to flash chromatography with simple examples, including definitions of RF, CV, and use of gradient chromatography and gradient flash chromatography.
Sep 22, 2017
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Environmental laboratories routinely evaluate VOCs in water via P&T GC-MS analysis. Because of the sensitivity of this method, it is critical that water used to prepare blanks, standards, and dilute samples be free of the VOCs to be analyzed. After purification by Milli-Q® water purification systems and a point-of-use VOC-Pak® cartridge, product water is free of any compounds that could interfere with P&T GC-MS analysis of VOC levels.
Sep 21, 2017
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By Advion
High-profile murder cases have forced forensic labs to improve detection of EDTA in blood. Learn how LC and a single-quad compact mass spectrometer can quickly screen.
Sep 20, 2017
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Cannabis testing labs typically analyze for the 5 to 10 most common cannabinoids. This method targets 11 cannabinoids, including THCV, with an instrument cycle time of less than 10 min. The high-efficiency chromatography produces sharp chromatographic peaks for the best overall sensitivity.
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