LCGC Blog

Sep 11, 2013
The LCGC Blog
By LCGC Editors
Tony Taylor provides insight on the best way to choose GC columns based on analyte or sample characteristics.
Sep 09, 2013
LCGC North America
By LCGC Editors
Researchers coupling high performance liquid chromatography to mass spectrometry face the challenge of segregating the ionized, typically nonvolatile analytes from a large amount of solvent, and the mobile phase is an important component in the process. LCGC Blog editor Kevin Schug discusses factors to consider when choosing a mobile phase for LC-MS.
Sep 05, 2013
LCGC Europe eNews
By LCGC Editors
Chromatography can be approximated by a series of equilibrium events between the mobile phase and stationary phase. Here, LCGC Blog editor Kevin Schug discusses an exceptional spreadsheet macro written by an undergraduate researcher that helps users visualize the development of chromatographic separations.
Aug 13, 2013
The LCGC Blog
By LCGC Editors
Chromatography can be approximated by a series of equilibrium events between the mobile phase and stationary phase. Here, LCGC Blog editor Kevin Schug discusses an exceptional spreadsheet macro written by an undergraduate researcher that helps users visualize the development of chromatographic separations.
Aug 06, 2013
The LCGC Blog
By LCGC Editors
Split/splitless injectors typically vaporise a sample dissolved in a suitable organic solvent under increased temperature. The sample vapours are entrained into the carrier gas flow inside a "liner" or "sleeve" within the inlet and from there pass into the column or out of the inlet via "split" line / valve. Splitless injection is used to perform an "on-instrument" dilution and the relative amounts of sample which enter the column or discarded to waste via the split line are adjusted using the relative carrier and split flow rate ratio.
Aug 01, 2013
LCGC Europe eNews
By LCGC Editors
J. Calvin Giddings provided one of the most practical discussions of the advantages of temperature programming in GC over isothermal analysis back in 1962. Here, Kevin Schug describes some of the salient points of that discussion and how they still apply today.
Jul 26, 2013
LCGC Europe eNews
By LCGC Editors
This month we take a look at the important topic of buffer choice for HPLC separations, how to the choose the correct buffer type and concentration as well as how to avoid variability in retention and selectivity.
Jul 10, 2013
The LCGC Blog
By LCGC Editors
J. Calvin Giddings provided one of the most practical discussions of the advantages of temperature programming in GC over isothermal analysis back in 1962. Here, Kevin Schug describes some of the salient points of that discussion and how they still apply today.
Jul 02, 2013
The LCGC Blog
By LCGC Editors
This month we take a look at the important topic of buffer choice for HPLC separations, how to the choose the correct buffer type and concentration as well as how to avoid variability in retention and selectivity.
Jun 07, 2013
The LCGC Blog
By LCGC Editors
It's important for chromatographers (particularly those who are also graduate students) to understand the fundamental aspects of separation science. In this installment of the LCGC Blog, Kevin Schug discusses the connection between thermodynamics and chromatography.
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