CHROMacademy

Mar 16, 2015
By LCGC Editors
HPLC troubleshooting guide to cycling baselines and pressure fluctuations from LCGC's ChromAcademy.
Feb 17, 2015
By LCGC Editors
Instrument manufacturers try to convince us that mass spec is just another detector. Most of us who work with LC-MS know that’s simply not the case – they can be maintenance intensive, unforgiving and generate complex information. When they’re not working it can be difficult to work out exactly where the problem lies. Here’s some advice to point you in the right direction
Feb 17, 2015
By LCGC Editors
A question about column dead volume. If the hold-up volume (time) is the extra-column dead volume expressed in time or volume. What is the column dead volume and how can it be calculated?
Jan 19, 2015
By LCGC Editors
CHROMacademy delivers key knowledge quickly in bite-size modules, and to prove this here is our seven point guide to understanding atmospheric pressure chemical ionization.
Dec 01, 2014
By LCGC Editors
It is of particular importance to reduce extra column volumes when using small volume columns or UHPLC. However, where do these extra column volumes come from, how can they be minimized, and what effect do they have on chromatography?
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