Column: Column Watch

Oct 31, 2017
LCGC North America
To resolve and quantitate monoclonal antibodies and antibody–drug conjugates, analytical scientists need various chromatographic modes, such as sizeexclusion, ion-exchange, hydrophobic interaction, and hydrophilic interaction chromatography. Here, we provide advice for making the most of each mode.
Sep 01, 2017
LCGC North America
Topics that stood out at HPLC 2017 include advances in large-molecule separations, multidimensional chromatography, HILIC, and chiral separations.
Jul 01, 2017
LCGC North America
A model set of analytes and selected applications are used to demonstrate the effects that buffers can have on the selectivity of a separation and the sensitivity of a reversed-phase analysis when using MS detection.
Jun 01, 2017
LCGC North America
In biphenyl phases, the surface chemistry often makes it possible to separate compounds not well resolved by C18 or phenyl phases.
Apr 01, 2017
LCGC North America
Our annual review of new liquid chromatography (LC) columns and accessories, including an analysis of the overall trends.
Feb 01, 2017
LCGC North America
This interactive classification map is a powerful tool for gaining useful knowledge about the properties of bonded LC stationary phases.
Dec 01, 2016
LCGC North America
The study shows results that promise to improve HILIC method development practices and provide insight into retention mechanisms across mechanistically different polar stationary phases.
Oct 01, 2016
LCGC North America
This test produces a classification map that can aid in column selection or in a quality-by-design approach to method development.
Sep 01, 2016
LCGC North America
At the 2016 HPLC symposium we saw interesting new developments in stationary phases (including 3D printing), high-speed chromatography, ion chromatography, and growing areas of application.
Jul 01, 2016
LCGC North America
Microscale LC–MS use is now feasible on a much wider scale.
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