Column: Column Watch

Jun 01, 2009
LCGC North America
Ron Majors provides an unbiased look at this present crisis and gives alternative solutions.
Apr 01, 2009
LCGC North America
Ron Majors brings readers the second part of his yearly review of all that was new and innovative at the annual Pittsburgh Conference.
Mar 01, 2009
LCGC North America
Ron Majors brings readers his yearly review of all that was new and innovative at the annual Pittsburgh Conference.
Jan 01, 2009
LCGC North America
Guest authors show how mixed modes can be used successfully in the optimization of protein purification, and discuss how various experimental parameters can be used to regulate the binding of proteins to mixed-mode sorbents.
Oct 01, 2008
LCGC North America
A variety of chromatographic sorbents are commercially available for reversed-phase liquid chromatography (RPLC) and while many of these columns are nominally similar, in practice the columns may provide significantly different separations.
Sep 01, 2008
LCGC North America
Ron Majors continues his summary of the technical highlights of HPLC 2008, discussing more hot topics from the show.
Aug 01, 2008
LCGC North America
HPLC 2008 was held in Baltimore in May. Columnist Ron Majors covers the highlights of this major symposium, held in the U.S. every two years.
Jul 01, 2008
LCGC North America
Guest Editor Peter Schoenmakers provides an introduction to LCxLC, and then goes on to talk about peak capacity, sample dimensionality, phase orthogonality, and some of the successes of the technique and the obstacles yet to be overcome.
Jun 01, 2008
LCGC North America
Guest columnsist and LCGC Emerging Leader award recipient Gert Desmet considers the different methods that can be used to compare the performance of LC columns.
May 01, 2008
LCGC Europe
By LCGC Editors
In this instalment of "Column Watch", columnist Ron Majors examines the role of pressure in high performance liquid chromatography (HPLC) from two viewpoints: the impact of the ultrahigh pressures encountered in ultrahigh-pressure liquid chromatography (UHPLC) on chromatographic parameters and increases in column pressure encountered in normal daily use. The latter is of more practical consequence to HPLC users because increased back pressure usually implies that something has gone wrong with the column. Pressure increases as a result of physical and chemical contamination are explored and practical approaches to solve these problems are suggested.
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