Column: Coupling Matters

May 01, 2012
LCGC Europe
A review of nomenclature and conventions used in comprehensive multidimensional chromatography. An update of the popular paper on this topic from 2003.
Oct 01, 2011
LCGC Europe
Describes a novel approach for the enantioselective separation of spearmint oil incorporating a fluidic modulation system.
Jun 01, 2011
LCGC Europe
This article describes a 2D matrix elimination ion chromatography method to analyse samples containing high levels of matrix ions.
Sep 01, 2010
LCGC Europe
Exploring the use of GCxGC-FID as a technique for qualitative and quantitative analysis of perfumes
Feb 01, 2010
LCGC Europe
Demonstrating the suitability of a new wax stationary phase for GCxGC analysis of essential oils
Nov 01, 2009
LCGC Europe
Mass spectrometry-based electronic nose technology (MS-nose technology) is a fast hyphenated technique for digital odour characterization of food and beverage products.
Jul 01, 2009
LCGC Europe
The trend in residue analysis has changed from target-oriented procedures towards accurate mass full-scan MS techniques. This article describes these developments and addresses the implications of 2002/657/EC.
May 01, 2009
LCGC Europe
Two-dimensional liquid chromatography (2D-LC) allows analysts to deal with complex samples that either cannot be adequately separated by one-dimensional liquid chromatography (1D-LC) or require excessively long analysis times. Peptide mixtures, whose characterization is relevant in many areas (e.g., proteomics, food analysis, pharmaceutical, life sciences), are a clear example of such complexity. An overview of the most used 2D-LC modes of operation is presented and several examples of their use for the separation of peptide mixtures are described.
Jan 01, 2009
LCGC Europe
The interpretation of comprehensive two-dimensional gas chromatography (GC×GC) based on the modulation ratio (MR) concept encompasses method implementation, ideas on quantitative measurement and how modulation phase affects GC×GC.
Nov 01, 2008
LCGC Europe
By LCGC Editors
Differential flow modulation is an inexpensive way to perform GC×GC separations which has been attracting growing attention recently. Differential flow modulation uses high carrier gas flow rates in the second dimension column so it is widely thought that this rules out direct coupling with mass spectrometry. However direct coupled GC×GC-QPMS using differential flow modulation is reported here for the first time using an unmodified mass spectrometer comprising a dual inlet turbomolecular pump and fast scanning quadrupole mass analyser. The suitability of the approach for characterization of essential oils is demonstrated.
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