Column: Perspectives in Modern HPLC

New HPLC Systems and Products Introduced at Pittcon 2015: A Brief Review

Apr 01, 2015
LCGC North America

This installment highlights noteworthy high performance liquid chromatography (HPLC) and related products introduced at Pittcon 2015 in New Orleans, Louisiana, as well as in the year prior.

HPLC for Characterization and Quality Control of Therapeutic Monoclonal Antibodies

Oct 01, 2014
LCGC North America

By Taylor Yonghua Zhang, Cynthia Quan, Michael W. Dong

The latest approaches to antibody characterization go beyond ion-exchange, size-exclusion, and reversed-phase modes to make use of affinity, hydrophobic interaction, mixed-mode, and HILIC techniques.

Seven Common Faux Pas in Modern HPLC

Aug 01, 2014
LCGC North America

By Michael W. Dong

Because of improved technologies and other changes in modern HPLC, these seven common practices are now highly questionable.

Superficially Porous Particles: Perspectives, Practices, and Trends

Jun 01, 2014
LCGC North America

By Szabolcs Fekete, Davy Guillarme, Michael W. Dong

An updated overview of the development of SPP technology, including benefits, limitations, and the theory behind its success

New HPLC Systems and Related Products Introduced at Pittcon 2014: A Brief Review

Apr 01, 2014
LCGC North America

By Michael W. Dong

Noteworthy new HPLC systems and related products

More Myths in Ultrahigh-Pressure Liquid Chromatography

Nov 01, 2013
LCGC Europe

By Michael W. Dong

This instalment describes more popular myths or half-truths in UHPLC and provides data that contradict or even repudiate some of these commonly held beliefs.

Myths in Ultrahigh-Pressure Liquid Chromatography

Oct 01, 2013
LCGC North America

By Michael W. Dong

A number of popular myths or half-truths in UHPLC are described and data are provided that contradict some of these commonly held beliefs.

A Three-Pronged Template Approach for Rapid HPLC Method Development

Aug 01, 2013
LCGC North America

By Michael W. Dong

HPLC method development can be accelerated by using three distinct method templates of increasing complexity.

The Essence of Modern HPLC: Advantages, Limitations, Fundamentals, and Opportunities

Jul 01, 2013
LCGC Europe

By Michael W. Dong

The reasons that make HPLC so ubiquitous; the fundamentals on how we conduct HPLC separations; and a few opportunities with far-reaching impacts in life sciences for separation scientists are discussed in this article.

The Essence of Modern HPLC: Advantages, Limitations, Fundamentals, and Opportunities

Jun 01, 2013
LCGC North America

By Michael W. Dong

The fundamental concepts of HPLC are re-examined.

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