Gas Chromatography (GC)

Jun 01, 2017
LCGC Europe
Some 50 years after Giddings’s iconic comparison of the separation speed of gas chromatography (GC) and liquid chromatography (LC), the authors revisit this comparison using kinetic plots of the current state‑of‑the-art systems in LC, supercritical fluid chromatography (SFC), and GC. It is found that, despite the major progress LC has made in the past decade (sub-2-µm particles, pressures up to 1500 bar, core–shell particles), a fully optimized ultrahigh-pressure liquid chromatography (UHPLC) separation is still at least one order of magnitude slower than capillary GC. The speed limits of packed bed SFC are situated in between.
May 01, 2017
LCGC North America
Annual review of new developments in the field of GC
Mar 01, 2017
LCGC North America
Changing just one variable at a time is often the best approach.
Feb 07, 2017
The Column
Recent advances in vacuum ultraviolet (VUV) spectroscopy have allowed for the application of this technology as a chemical detection platform for gas chromatography (GC). This technique is known as GC–VUV. A GC–VUV detector can produce highly characteristic absorbance spectra for nearly all chemical species in the wavelength region of 125–240 nm. This enables not only identification but also robust quantitation of a variety of compounds separable by gas chromatography, including water. This article describes the results of a pilot study focused on trace water determination in common organic solvents using an ionic liquid stationary phase GC column in a GC–VUV platform.
Feb 01, 2017
LCGC North America
The most prominent advantage of using nitrogen as a carrier gas is that it is the most efficient one when used at its optimum linear velocity.
Jan 01, 2017
LCGC North America
We examine the experimental factors that control peak resolution.
Nov 01, 2016
LCGC North America
What are the best procedures for safe setup, use, and disposal of compressed gas cylinders in the chromatography laboratory?
Oct 01, 2016
LCGC North America
What are the principal hazards and safety issues surrounding high-pressure gas cylinders?
Jul 01, 2016
LCGC North America
Choosing the wrong septa can compromise method accuracy.
May 20, 2016
LCGC Europe
Chromatography connected with ion mobility spectrometry (IMS) is not commonly used, but is being investigated more. IMS is an independent analytical technique with very good detectability and a rather small separation ability. One favourable property of IMS is that it can work with ambient pressure and can be easily connected to a gas chromatograph. Analytical applications of GC–MS are very different and encompass investigations into food, medical science, environment, drugs of abuse, chemical warfare agents, and explosives.
lorem ipsum