Gas Chromatography (GC)

Jul 01, 2016
LCGC North America
Choosing the wrong septa can compromise method accuracy.
May 20, 2016
LCGC Europe
Chromatography connected with ion mobility spectrometry (IMS) is not commonly used, but is being investigated more. IMS is an independent analytical technique with very good detectability and a rather small separation ability. One favourable property of IMS is that it can work with ambient pressure and can be easily connected to a gas chromatograph. Analytical applications of GC–MS are very different and encompass investigations into food, medical science, environment, drugs of abuse, chemical warfare agents, and explosives.
May 01, 2016
LCGC North America
The number and type of new product introductions this year are an indication of the continuing viability of gas chromatography.
May 01, 2016
LCGC North America
How would you analyze a bag of gummy bears that showed up on your laboratory bench? This was the challenge taken on by teams of analysts in advance of the Conference on Small Molecule Science (CoSMoS) that was held in August 2015 in San Diego, California. This article shares insights from how the finalists approached the question.
Apr 27, 2016
The Column
Incognito shares his thoughts on the importance of specifications for method transfer in gas chromatography (GC).
Apr 20, 2016
The Column
Jack Cochran’s new column “Practical GC” provides readers with practical advice and new experimental evidence for how to get the best results from their gas chromatography (GC) systems. This instalment looks at understanding and using split ratio for “shoot and dilute” GC.
Mar 21, 2016
The Column
Gas chromatography (GC) is an established and well-understood technique. As the cannabis industry grows, demand for analytical robustness is increasing for analytes such as pesticides, residual solvents, and terpenes. GC and GC coupled to mass spectrometry (GC–MS) are effective tools to address the demands of laboratories, growers, manufacturers, and consumers. This article provides an overview of the types of compounds that can be analyzed by GC, reviews the strengths and weaknesses of the analytical methods, and discusses areas of opportunity for chromatography.
Mar 17, 2016
The Column
This article describes the use of a headspace thermal desorption–gas chromatography–time-of-flight mass spectrometry (headspace TD–GC–TOF-MS) method to analyze complex aroma profiles from hops, and highlights how it can provide a rapid yet robust approach when comparing similar samples. The article also examines the potential of “soft” electron ionization at 12 eV for distinguishing between structurally similar monoterpenoids and sesquiterpenoids to provide better characterization of the often subtle differences in headspace profiles between different hop varieties.
Mar 01, 2016
LCGC North America
The terms carrier-gas flow and velocity are often used interchangeably when discussing column parameters. In LC, the two terms scale together, but in GC they do not. How does this nonintuitive behavior affect best practices for gas chromatographers?
Mar 01, 2016
LCGC North America
When monitoring toxic gases emitted from the soil, it is often necessary to recover compounds with a boiling point above that of napthalene. The use of thermal desorption makes that possible.
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