LC-20AP – a new preparative HPLC pump

Mar 26, 2010
By LCGC Editors

Shimadzu introduces the next generation LC-20AP Preparative LC pump, suitable for analytical, semi-prep and prep LC applications without changing pump heads.

The wide flow rate range (0.01 – 150 mL/min) with high pressure tolerance (420 bar up to 100 mL/min and 300 bar up to 150 mL/min) enables the use of 50 mm ID x 250 mmL 5 µm-particle size columns to achieve high-resolution and high-efficiency purification, leading to an improvement in productivity of five to ten times that of the previous models. The flow rate accuracy and precision were drastically improved by minimizing dead volume in the pump heads and using higher resolution micro-stepping motor control so that the pump can be used at an analytical flow rate range, such as 1 mL/min, with high reliability.

Overall productivity and quality of the purification has also been greatly improved. When configured as an analytical/prep system, users can develop a method at analytical scale and then convert the method immediately for prep scale. Shimadzu provides a tool to convert methods easily between analytical and prep for support customers. In addition, the LC-20AP pump can be used with Open Solution automated prep LC/MS software, allowing researchers to purify their compounds by simplifying the workflow in a walk-up environment.

Shimadzu has also reacted to environmental concerns. LC-20AP saves 40% energy in comparison with the previous model thanks to a newly designed high-efficiency power supply and motor control electronics. This makes the product more ecological.

For further details please visit