The LCGC Blog

Jan 20, 2015
The LCGC Blog
By LCGC Editors
If you do Gas Chromatography, then you will have undoubtedly conditioned a capillary GC column ready for use after a period of storage or before first use.
Jan 19, 2015
The LCGC Blog
By LCGC Editors
If you do Gas Chromatography, then you will have undoubtedly conditioned a capillary GC column ready for use after a period of storage or before first use.
Jan 14, 2015
The LCGC Blog
I have had enough conversations with experts in the field of high performance liquid chromatography (HPLC) stationary-phase supports to know that there is more to the increased efficiency provided by the use of superficially porous particles (SPP) compared to fully porous particles (FPP) than simply mass transfer effects. Yet, I would argue that this is still one of the biggest misconceptions propagated by some members of the chromatography community.
Dec 18, 2014
E-Separation Solutions
By LCGC Editors
In this issue – I hope to outline some 'small bolts' that are commonly ignored in everyday chromatography and mass spectrometry - instrument settings that I have to come call 'lock and leave' parameters. We can generate data without changing them or paying them any attention, but how much better could our data be if we bothered to optimise them.
Dec 10, 2014
E-Separation Solutions
A program was formulated to help educate public opinion leaders on the fundamentals of unconventional natural gas and oil extraction, to convey the current state of research on the topic, and to disseminate and discuss prospective regulations that have been formulated over the past two to three years.
Nov 18, 2014
LCGC North America
By LCGC Editors
Much has been written about options for increasing efficiency in HPLC ? primarily through the use of core shell and sub 2 ?m particles, which have been used to increase efficiency, speed up separations or increase peak capacity. However, many separations can only be effectively improved, by optimising selectivity ? resolution is a function of selectivity, efficiency and retention, with selectivity being the most effective at achieving good resolution.
Nov 12, 2014
E-Separation Solutions
By LCGC Editors
I will preface this blog installment by saying that I am not an expert on separation of proteins, but I am learning. What I do understand are the fundamentals of chromatography for small molecules. This information abounds, but it is much more difficult to find the same level of information for biomacromolecule chromatography.
Oct 15, 2014
The LCGC Blog
By LCGC Editors
Why would one want to use a mobile phase containing 100% water? Usually to wash the analyte or old mobile phase from the column (stationary phase surface) or to help retain analytes which elute quickly using mobile phases containing only very small amounts of organic solvent (usually highly polar analytes).
Oct 08, 2014
By LCGC Editors
Unconventional oil and gas (UOG) extraction, which includes processes such as horizontal drilling and hydraulic fracturing, has created major positive geopolitical and economic advantages for the United States.
Sep 17, 2014
E-Separation Solutions
By LCGC Editors
Most of us who have used UV detection for HPLC analyses consider them very straightforward and find they produce fit for purpose data whenever we need them to.
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