Tips & Tricks: GPC/SEC How to Get a Stable Baseline -

Tips & Tricks: GPC/SEC How to Get a Stable Baseline - - Chromatography Online

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Tips & Tricks: GPC/SEC How to Get a Stable Baseline

Apr 2, 2012
By: Daniela Held
The Column
Volume 8, Issue 6

A stable baseline is a prerequisite for precise, accurate and reproducible GPC/SEC analysis, especially for samples with a broad molar mass distribution. Baseline problems can include drift, wander (long-term noise), noise/spikes (short-term noise), as well as positive or negative system peaks.

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