May 2, 2012
By:Glenn Cudiamat
Supercritical fluid chromatography (SFC) makes use of a supercritical fluid, typically carbon dioxide (CO2), instead of an organic or aqueous solvent, to carry the sample through the chromatography column.
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May 2, 2012
Janet Kelsey of The Column spoke to Joe Anacleto, Vice President of Applied Markets, AB Sciex, and Sky Countryman, Manager, Applied Markets Research Team, Phenomenex, about the impact their companies? joint collaboration project will have on the food safety testing market.
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 | May 2, 2012
By:Jeremy Ratel, Erwan Engel
It is well established that food-producing animals are exposed to toxic micropollutants via environment and feeds, and that micropollutants entering the animals are transferred to edible tissues, thus representing a chemical human health hazard.
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May 2, 2012
By:Maria Rambla-Alegre, Samuel Carda-Broch, Josep Esteve-Romero
Veterinary drugs have become an integral part of livestock production and play an important role in animal welfare maintenance, mainly for preventing disease, curing infection, controlling the risk of disease transmission to humans and for increasing the productive capacity of animals.
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April 19, 2012
By:Kelly Ke Zhang, Midco Chi-Ying Tsang
Automated column and mobile phase screening is the current trend in the pharmaceutical industry to develop chiral methods. This study presents comprehensive strategies for automated rapid chiral HPLC method development including normal-phase, reversed-phase and polar organic phase separation modes.
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April 19, 2012
By:Rainer Bauder, Felicity Kusinitz, David Thomas, Frank Steiner
LC method development for new drug candidates or screening methods for new active structures in botanicals present the same type of challenges: How do I know that I have separated all main components, as well as important, sometimes hidden, impurities? Is my resolution good enough? Am I missing small, co-eluting peaks?
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April 19, 2012
By:Incognito
Ask yourself a simple question. Do you know the structure or any of the physical properties of the analyte(s) from your most recent analysis? If the answer is yes, award yourself a self-congratulatory point. If no, why on earth not?
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April 19, 2012
By:Scott Fulton
The growing importance of biotherapeutics to the pharmaceutical industry has created an increasing demand for protein analysis techniques with high precision, high sensitivity and high throughput. These techniques are used throughout the development process, starting with the discovery phase and continuing into lead optimization and characterization, preclinical and clinical trials (for both the biotherapeutic itself and related protein biomarkers) and manufacturing process development and control.
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 | April 12, 2012
By:James S. McKenzie, Julie C. Wilson, Jane E. Thomas-Oates, Adrian J. Charlton
Traditional approaches for measuring food components are based on a ?target list? approach, whereby specific methodologies are developed for individual or related compounds. Such methods are well-suited for routine monitoring but can fail to detect emerging contamination events or to identify new prospects for product development.
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