Current Articles - Chromatography Online
Current Articles

Seven Common Faux Pas in Modern HPLC

August 1, 2014

Because of improved technologies and other changes in modern HPLC, these seven common practices are now highly questionable.

How Much Retention Time Variation Is Normal?

August 1, 2014

Small changes in retention time with an LC method are normal. At what point is a problem suggested?

Modern Mass Spectrometry in Protein Analysis

August 1, 2014

An overview of the analytical approaches used for the analysis of biomolecules

Standardized Testing of Silica as a Base Material for Difficult Bonded-Phase Preparative Applications

August 1, 2014

Mechanical strength, acid and alkaline durability, loadability, and overload characteristics are a few of the parameters evaluated.

Electrophoretic and Microfluidic Separation Approaches for DNA Analysis

July 1, 2014

Kevin Dorfman discusses his work to improve electrophoresis and nanochannel technologies to obtain genomic information.

Professor Barry L. Karger: Scientist, Mentor, and Innovator

July 1, 2014

A review of Professor Barry L. Karger's years as a teacher and mentor, as well as his many scientific accomplishments

Mobile-Phase Degassing: What, Why, and How

July 1, 2014

Why should you be concerned about mobile-phase degassing?

Highlights of HPLC 2014

July 1, 2014

Highlights of the discussions on column-technology topics — such as monoliths, high-pH columns, SPPs, and HILIC — and an analysis of the larger trends observed at the conference.

Gas Cylinder Setup and Use

July 1, 2014

What you need to know about pressure regulators, gas filtration, and gas fittings — and when to retire your cylinders

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LCGC COLUMNISTS 2014

Column Watch | Ronald E. Majors: Ron Majors, established authority on new column technologies, keeps readers up-to-date with new sample preparation trends in all branches of chromatography and reviews developments. LATEST: Standardized Testing of Silica as a Base Material for Difficult Bonded-Phase Preparative Applications


Perspectives in Modern HPLC: Michael W. Dong is a senior scientist in Small Molecule Drug Discovery at Genentech in South San Francisco, California. He is responsible for new technologies, automation, and supporting late-stage research projects in small molecule analytical chemistry and QC of small molecule pharmaceutical sciences. LATEST: Seven Common Faux Pas in Modern HPLC


MS — The Practical Art: Kate Yu brings her expertise in the field of mass spectrometry and hyphenated techniques to the pages of LCGC. In this column she examines the mass spectrometric side of coupled liquid and gas-phase systems. Troubleshooting-style articles provide readers with invaluable advice for getting the most from their mass spectrometers. LATEST: Radical Mass Spectrometry as a New Frontier for Bioanalysis


LC Troubleshooting: LC Troubleshooting sets about making HPLC methods easier to master. By covering the basics of liquid chromatography separations and instrumentation, John Dolan is able to highlight common problems and provide remedies for them. LATEST: How Much Retention Time Variation Is Normal?


More LCGC Chromatography-Related Columnists>>

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