High Throughput Analysis for Food Safety and Cosmetics - - Chromatography Online
High Throughput Analysis for Food Safety and Cosmetics

Meeting Reports

Session 1260, Room 504bc, 1:30 p.m.

This Tuesday afternoon session was arranged by Perry G. Wang of the U.S. Food and Drug Administration (US FDA) and Mark F. Vitha of Drake University.

Vitha will preside over the session and start things off with his presentation titled “High Throughput Techniques for Food Analysis.” This presentation will provide an overview of high throughput food analysis and is intended to provide a general context for understanding the subsequent, more specific presentations that follow in the session.

Next, Wanlong Zhou of the US FDA will present a talk titled “Rapid and Simultaneous Determination of Harmful Chemicals in Nail Products by Gas Chromatography-Tandem Mass Spectrometry.” Zhou will discuss a rapid and sensitive gas chromatography–tandem mass spectrometry (GC–MS-MS) method that has been developed and validated to determine the level of harmful chemicals in nail products such as toluene, methylpyrrolidone, benzophenone-1, and diethylene glycol dimethacrylate.

The third talk in this session, Antibiotic Residue Detection by LC/MS/MS in Food,” will be given by Angela Carlson of SGS North America. Carlson will discuss the detectition of many classes of antibiotics in various food matrices that can be achieved using solid phase extraction (SPE) cleanup and analysis by high performance liquid chromatography with tandem mass spectrophotometry (HPLC–MS-MS).

Next, Xiang Zhang of the University of Louisville will give a talk titled “Impact of Chronic Ethanol Consumption on Metabolite Profiles of Liver in Mice: A Time Course Study.” Zhang will discuss the results of an investigation on the impact of chromic ethanol consumption on metabolite profiles of mouse liver. The derivatized samples were analyzed on a comprehensive two-dimensional gas chromatography time-of-flight mass spectrometer. The experimental data were first analyzed using the instrument software ChromaTOF for peak picking and compound identification, followed by MetPP software for retention index matching, alignment, normalization, quantification, and time course analysis.

After a brief recess, Pei Chen of the USDA with present a talk titled “A Mass Spectroscopic Fingerprinting Method for Authentication and Quality Assessment of Scutellaria lateriflora Based Dietary Supplements.” In this study, a flow injection electrospray ionization-mass spectrometry (ESI-MS) fingerprinting method in combination with principal component analysis (PCA) was used to survey Scutellaria lateriflora-based dietary supplements sold in the US.

Next, James Chang of Thermo Fisher Scientific will present “Micro Flow LC and its Application on Food Safety Analysis.” This paper presents an application of ultra-high performance liquid chromatography (UHPLC) and micro flow liquid chromatography (MFLC) coupled with electrospray ionization (ESI) quadrupole Orbitrap high resolution mass spectrometry (Q-Orbitrap) for the determination of ~500 pesticide residues in fruits and vegetables.

Finally, Kelly Dorweiler of General Mills/Medallion Laboratories will give a presentation titled “Improving Identification of Pesticides Using Atmospheric Pressure Gas Chromatography Coupled with Mass Spectrometry.” Dorweiler will discuss how atmospheric pressure ionization gas chromatography (APGC) provides a softer ionization of the analyte, preserving the molecular ion for better identification. Results will be presented including signal-to-noise of the molecular ions and key fragments for complex matrices including flaxseed and dried soybean.

Following the final presentation there will be an open discussion with the speakers and audience.


blog comments powered by Disqus
LCGC E-mail Newsletters
Global E-newsletters subscribe here:



Column Watch: Ron Majors, established authority on new column technologies, keeps readers up-to-date with new sample preparation trends in all branches of chromatography and reviews developments. LATEST: When Bad Things Happen to Good Food: Applications of HPLC to Detect Food Adulteration

Perspectives in Modern HPLC: Michael W. Dong is a senior scientist in Small Molecule Drug Discovery at Genentech in South San Francisco, California. He is responsible for new technologies, automation, and supporting late-stage research projects in small molecule analytical chemistry and QC of small molecule pharmaceutical sciences. LATEST: HPLC for Characterization and Quality Control of Therapeutic Monoclonal Antibodies

MS — The Practical Art: Kate Yu brings her expertise in the field of mass spectrometry and hyphenated techniques to the pages of LCGC. In this column she examines the mass spectrometric side of coupled liquid and gas-phase systems. Troubleshooting-style articles provide readers with invaluable advice for getting the most from their mass spectrometers. LATEST: Radical Mass Spectrometry as a New Frontier for Bioanalysis

LC Troubleshooting: LC Troubleshooting sets about making HPLC methods easier to master. By covering the basics of liquid chromatography separations and instrumentation, John Dolan is able to highlight common problems and provide remedies for them. LATEST: How Much Can I Inject? Part I: Injecting in Mobile Phase

More LCGC Columnists>>

LCGC North America Editorial Advisory Board>>

LCGC Europe Editorial Advisory Board>>

LCGC Editorial Team Contacts>>

Source: Meeting Reports,
Click here