The Australian Patent Office has granted a patent related to W. R. Grace & Company’s (Columbia, Maryland) Reveleris flash chromatography system. The patent concerns the use of evaporative light scattering detection (ELSD) with flash chromatography. The technology covered in this allowed claim enables streamlined purification of new chemical and biological entities for drug discovery.
Grace previously received similar U.S. patents related to various aspects of flash chromatography using two kinds of detectors, such as ELSD and UV, to collect sample fractions. These techniques improve new molecule purification by increasing recovery, improving reliability, and simplifying instrument operation.