How much can you purify with a lab-scale LC? - - Chromatography Online
How much can you purify with a lab-scale LC?

LCGC Europe eNews

Introducing the flexible Contichrom® lab process equipment

Contichrom® lab is a preparative 2-column liquid chromatography system designed for discovery, process development and scale-up, offering great flexibility for all process choices (batch, SMB, MCSGP, multi-column) using a single equipment and control software.

Fast process development for an optimized process is being achieved by omitting large screening efforts and instead starting from a simple non-optimized batch process that is switched to a superior MCSGP process by the user-friendly Contichrom® lab control software.

The MCSGP process principle uses twin columns instead of one, whereby the impure side fractions containing product are recycled internally extracting all product, thereby increasing both yield and purity by 50% at a 10-fold throughput increase and 70% buffer reduction.

All standard resin and column formats (RP, HIC, IEX, SEC) can be used from low-high pressure with full solvent compatibility.

Contichrom® lab has been designed to be very user-friendly employing software that helps the user to navigate through the process setup, execution and reporting, being 21CFR part 11 compliant.

Is your LC purification system equally adaptable?

Learn more about LC purification with Contichrom at


LCGC E-mail Newsletters
Global E-newsletters subscribe here:



Column Watch: Ron Majors, established authority on new column technologies, keeps readers up-to-date with new sample preparation trends in all branches of chromatography and reviews developments. LATEST: When Bad Things Happen to Good Food: Applications of HPLC to Detect Food Adulteration

Perspectives in Modern HPLC: Michael W. Dong is a senior scientist in Small Molecule Drug Discovery at Genentech in South San Francisco, California. He is responsible for new technologies, automation, and supporting late-stage research projects in small molecule analytical chemistry and QC of small molecule pharmaceutical sciences. LATEST: HPLC for Characterization and Quality Control of Therapeutic Monoclonal Antibodies

MS — The Practical Art: Kate Yu brings her expertise in the field of mass spectrometry and hyphenated techniques to the pages of LCGC. In this column she examines the mass spectrometric side of coupled liquid and gas-phase systems. Troubleshooting-style articles provide readers with invaluable advice for getting the most from their mass spectrometers. LATEST: Radical Mass Spectrometry as a New Frontier for Bioanalysis

LC Troubleshooting: LC Troubleshooting sets about making HPLC methods easier to master. By covering the basics of liquid chromatography separations and instrumentation, John Dolan is able to highlight common problems and provide remedies for them. LATEST: How Much Can I Inject? Part I: Injecting in Mobile Phase

More LCGC Columnists>>

LCGC North America Editorial Advisory Board>>

LCGC Europe Editorial Advisory Board>>

LCGC Editorial Team Contacts>>

Source: LCGC Europe eNews,
Click here