Dispersive Liquid-Liquid Microextraction of Antibacterial Agent
Jan 15, 2009
Researchers from Universidad de Santiago de Compostela (Santiago de Compostela, Spain) developed a dispersive liquid-liquid microextraction sample preparation method to determine the antibacterial agent triclosan and its environmental transformation product methyl triclosan in water samples. The extraction used a ternary mixture of a disperser, an extractant, and a derivatization reagent. Simultaneous derivatization and concentration of both species was achieved. The analysis was performed using gas chromatography with tandem mass spectrometry.
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Perspectives in Modern HPLC: Michael W. Dong is a senior scientist in Small Molecule Drug Discovery at Genentech in South San Francisco, California. He is responsible for new technologies, automation, and supporting late-stage research projects in small molecule analytical chemistry and QC of small molecule pharmaceutical sciences. LATEST: Seven Common Faux Pas in Modern HPLC