Current Articles - Chromatography Online
Current Articles

Ultrahigh-Performance Liquid Chromatography–Mass Spectrometry in Lipidomics

April 1, 2014

An analytical method for the global profiling of molecular lipids in biological samples, with particular emphasis on the plasmalogen lipids, is described.

The Role of Chromatography in the Characterization and Analysis of Protein Therapeutic Drugs

April 1, 2014

Chromatography has taken a prominent place in the characterization and analysis of protein therapeutic drugs and today it plays a critical role in the biotechnology laboratory.

New Chromatography Columns and Accessories at Pittcon 2014, Part I

April 1, 2014

New product introductions in the areas of HPLC columns for reversed-phase LC, HILIC, ion-exchange and ion chromatography, SEC, and specialty columns for specific types of analyses are covered.

The 2014 LCGC Awards

April 1, 2014

The winners of LCGC's seventh annual awards are highlighted.

Metabolomics in Food and Nutrition Laboratories

April 1, 2014

A look at the various strategies and tools related to metabolomics applied to food and nutrition

Comparison of Edible Oils by GCxGC–TOF-MS and GC–High Resolution TOF-MS for Determination of Food Fraud: A "Foodomics" Approach

March 1, 2014

Here, a method to characterize edible oils and edible oil mixtures through fingerprinting and the isolation of individual analyte differences is reported. Aroma and flavor analytes in extra virgin olive, olive, peanut, grapeseed, and vegetable oils were sampled with headspace solid-phase microextraction (HS-SPME).

Application of Pyrolysis–Gas Chromatography–Mass Spectrometry for the Identification of Polymeric Materials

March 1, 2014

This pyrolysis–GC–MS method enables direct analysis of solid or liquid polymers without sample pretreatment, as illustrated here for various materials, including a dental filling material and a car wrapping foil.

Application of Mass Spectrometry to Support Verification and Characterization of Counterfeit Pharmaceuticals

March 1, 2014

The production and sale of counterfeit drugs has risen sharply in recent years. The World Health Organization (WHO) estimates that counterfeit medicines account for approximately 1% of sales in developed countries and well over 10% in developing countries.

Analysis of Amphetamines and Synthetic Cathinones in Hair Samples Using LC–Tandem Mass Spectrometry and Solid-Phase Extraction

March 1, 2014

An efficient method for forensic analysis of amphetamines and synthetic cathinones — the illicit drugs often called "bathsalts" — in hair samples

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LCGC COLUMNISTS 2014

Sample Prep Perspectives | Ronald E. Majors: Ron Majors, established authority on new column technologies, keeps readers up-to-date with new sample preparation trends in all branches of chromatography and reviews developments.
LATEST: UV Detector Problems


Perspectives in Modern HPLC | Michael W. Dong: Michael W. Dong is a senior scientist in Small Molecule Drug Discovery at Genentech in South San Francisco, California. He is responsible for new technologies, automation, and supporting late-stage research projects in small molecule analytical chemistry and QC of small molecule pharmaceutical sciences. LATEST: Superficially Porous Particles: Perspectives, Practices, and Trends


MS — The Practical Art | Kate Yu: Kate Yu brings her expertise in the field of mass spectrometry and hyphenated techniques to the pages of LCGC. In this column she examines the mass spectrometric side of coupled liquid and gas-phase systems. Troubleshooting-style articles provide readers with invaluable advice for getting the most from their mass spectrometers. LATEST: Radical Mass Spectrometry as a New Frontier for Bioanalysis


LC Troubleshooting | John Dolan: LC Troubleshooting sets about making HPLC methods easier to master. By covering the basics of liquid chromatography separations and instrumentation, John Dolan is able to highlight common problems and provide remedies for them. LATEST: Problems with Large-Molecule Separations


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