May 1, 2013
By:
John W. Dolan
Sometimes when changes are made to gradient conditions, the result isn't what was expected.
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Apr 1, 2013
By:
John W. Dolan
Is it possible to get the same separation under isocratic and gradient conditions?
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Mar 1, 2013
By:
John W. Dolan
In contrast to isocratic separations, gradient elution can sometimes seem to be counter-intuitive. Yet with the proper perspective, the things we intuitively understand about isocratic methods apply in a similar manner to gradients.
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Feb 1, 2013
By:
John W. Dolan
It is important to consider the influence of the sample matrix when setting up an analytical method
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Feb 1, 2013
By:
John W. Dolan
How to account for the sample matrix when developing a method
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Jan 1, 2013
By:
John W. Dolan
How to choose conditions and what to do with the results
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Jan 1, 2013
By:
John W. Dolan
The use of a gradient scouting run can be a powerful tool to jump-start method developent. But what conditions should be chosen, and what do we do with the results?
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Dec 1, 2012
By:
John W. Dolan
A description of how refractive index detectors work and some good practices to get the most out of this powerful detector
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Dec 1, 2012
By:
John W. Dolan
The refractive index detector can be frustrating to use because of its extreme sensitivity to temperature and other variables. However, it can see things that no other detector can see.
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