Articles by Ronald E. Majors - Chromatography Online
Articles by Ronald E. Majors

Ronald E. Majors

"Column Watch" and "Sample Prep Perspectives" Editor

Ron Majors, editor of "Column Watch" and "Sample Prep Perspectives," has been with LCGC North America for over 26 years. Currently a senior scientist with Agilent Technologies, Wilmington, Delaware, Ron is known industry-wide as one of the premier chromatography experts in the field. He is also a member of LCGC's editorial advisory board.

Articles
When Bad Things Happen to Good Food: Applications of HPLC to Detect Food Adulteration
November 1, 2014

In this instalment, guest authors Jeff Hurst and Kendra Pfeifer from Hershey Foods explore high performance liquid chromatography (HPLC), ultrahigh-pressure liquid chromatography (UHPLC), and mass spectrometry (MS) approaches being adopted to keep ahead of the food adulteration game.

Highlights of HPLC 2014
September 1, 2014

This year's HPLC symposium was held in New Orleans, Louisiana, USA. In this review, Ron Majors covers HPLC and UHPLC column and sample preparation highlights, summarizes the awards presented, and reviews the overall liquid-phase chromatography trends.

Avoiding Reversed-Phase Chromatography Problems Through Informed Method Development Practices: Choosing the Stationary-Phase Chemistry
September 1, 2014

Many problems encountered executing HPLC methods are a result of decisions made during early method development. This article discusses one critical variable in method development, the choice of stationary phase chemistry.

Standardized Testing of Silica as a Base Material for Difficult Bonded-Phase Preparative Applications
August 1, 2014

Mechanical strength, acid and alkaline durability, loadability, and overload characteristics are a few of the parameters evaluated.

Standardized Testing of Silica as a Base Material for Difficult Bonded-Phase Preparative Applications
August 1, 2014

In HPLC column development, the bonded-phase silica is often only investigated to determine the suitability of a packed column for a particular separation class and not much thought is given to optimization of the base silica to make the overall packing material more suitable for the assay. Here, the authors examine general-purpose standardized tests to determine the quality of bulk silica before and after bonding.

Highlights of HPLC 2014
July 1, 2014

This year's symposium was held in New Orleans, Louisiana, USA. In this review, Ron Majors covers HPLC and UHPLC column and sample preparation highlights, summarizes the awards presented, and reviews the overall liquid-phase chromatographic trends.

Highlights of HPLC 2014
July 1, 2014

Highlights of the discussions on column-technology topics — such as monoliths, high-pH columns, SPPs, and HILIC — and an analysis of the larger trends observed at the conference.

Exploring the Possibilities of High-Throughput Sample Preparation
June 1, 2014

Sample preparation has often been viewed as the bottleneck in analytical procedures. Surveys have shown that time is typically the most frequent problem area for sample preparation procedures. While newly developed extraction techniques address time, modern chromatography advances are also moving towards faster separations. Based on these considerations, what is high-throughput sample preparation? Do modern extraction methods adequately address the issue of time? How can we address the analytical need for speed?

Introduction: Recent Developments in Sample Preparation
May 2, 2014

This month's "LC Troubleshooting" instalment looks at two reader-submitted questions regarding method calibration.

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LCGC COLUMNISTS 2014

Column Watch: Ron Majors, established authority on new column technologies, keeps readers up-to-date with new sample preparation trends in all branches of chromatography and reviews developments. LATEST: When Bad Things Happen to Good Food: Applications of HPLC to Detect Food Adulteration


Perspectives in Modern HPLC: Michael W. Dong is a senior scientist in Small Molecule Drug Discovery at Genentech in South San Francisco, California. He is responsible for new technologies, automation, and supporting late-stage research projects in small molecule analytical chemistry and QC of small molecule pharmaceutical sciences. LATEST: HPLC for Characterization and Quality Control of Therapeutic Monoclonal Antibodies


MS — The Practical Art: Kate Yu brings her expertise in the field of mass spectrometry and hyphenated techniques to the pages of LCGC. In this column she examines the mass spectrometric side of coupled liquid and gas-phase systems. Troubleshooting-style articles provide readers with invaluable advice for getting the most from their mass spectrometers. LATEST: Radical Mass Spectrometry as a New Frontier for Bioanalysis


LC Troubleshooting: LC Troubleshooting sets about making HPLC methods easier to master. By covering the basics of liquid chromatography separations and instrumentation, John Dolan is able to highlight common problems and provide remedies for them. LATEST: How Much Can I Inject? Part I: Injecting in Mobile Phase


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