Articles by Scott Peterman - Chromatography Online
Articles by Scott Peterman

Scott Peterman


Scott Peterman is with Proteomics Marketing Thermo Fisher Scientific, San Jose, California.

Articles
Use of Synthetic Peptides to Determine Relative Retention Times for Automated Targeted Protein/Peptide Quantification Method Development
October 4, 2012

Protein/peptide discovery data obtained from data-dependent experiments have been used to increase the success rate of targeted quantification assays as well as automate method building.

Targeted Quantitative Protein Analysis in Human Serum Using High-Resolution Multiple Selected Reaction Monitoring Assays
April 1, 2007

A common endpoint for a biomarker discovery experiment is a list of putative marker proteins. The next step is then to perform targeted quantitative measurements of these proteins in an expanded patient population to assess their validity as markers. Analytical accuracy and precision are required for unambiguous quantitative analysis of targeted proteins from very complex mixtures. Wide dynamic range and high sensitivity are critical for detecting low-abundance proteins. Such an assay also is appropriate for "targeted discovery" experiments, where the goal is to quantitate a large number (up to hundreds) of known proteins in a complex sample.

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