Articles by Chris Broomell

Chris Broomell

Characterization of Antibody-Drug Conjugates by SEC with Combined Light Scattering, dRI and UV Detection
January 15, 2013
By: Chris Broomell

There has been a significant resurgence in the development of antibody-drug conjugates (ADC) as target-specific therapeutic agents for cancer treatments. This article presents a method for DAR determination based on size-exclusion chromatography with multi-angle light scattering (SEC?MALS) combined with ultraviolet (UV) absorption and differential refractive index (dRI) detection.

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