Articles by Bethany Degg - Chromatography Online
Articles by Bethany Degg

Bethany Degg

Assistant Editor

Detecting Ignitable Liquids with GC–MS
July 24, 2014

Scientists from the National Institute of Standards and Technology (NIST) have demonstrated the application of PLOT-cryoadsorption (PLOT–cryo) coupled to gas chromatography–mass spectrometry (GC–MS) for the analysis of ignitable liquid (IL) residues in fire debris.

GC–MS Analysis of Blowflies to Detect Methamphetamine
July 24, 2014

Researchers from the University of Western Australia's Centre for Forensic Science have collaborated with the University of Turin's Department of Chemistry in Italy to develop a gas chromatography–mass spectrometry (GC–MS) method to analyze levels of methamphetamine (MA) in blowflies (Calliphora vomitoria L.).

Antimicrobial Exposure of Expectant Mothers
July 24, 2014

Liquid chromatography–mass spectrometry (LC–MS) analysis has been performed on urine and cord blood samples from expectant mothers to explore the exposure to the antimicrobial agents triclosan (TCS) and tricarban (TCC). The agents have received increasing attention over recent years, with concerns being raised over lack of efficacy and potential toxicity to the environment, as well as human health.

Digital Microfluidics Coupled to Miniature MS
July 24, 2014

Great advances have been made in the field of miniaturization of mass spectrometers, opening up the potential to save time by performing analysis in the field; however, sample preparation has yet to catch up. A new study published in the journal Analytical Chemistry demonstrates the application of microfluidics integrated with a miniature mass spectrometer for the detection of illicit drugs in dried urine samples, which can simultaneously analyze four samples in under 15 min.

HPLC–MS–MS Detects Insecticide Degradates in Baby Food
July 7, 2014

Scientists from Emory University (Georgia, USA) have developed a new solid–phase extraction (SPE) method to isolate four insecticide degradates from baby food for analysis by high performance liquid chromatography tandem mass spectrometry (HPLC–MS–MS). The paper published in the Journal of Agricultural and Food Chemistry describes how the method can be applied to differentiate between exposure to insecticides or preformed degradates.

N–glycan Biopharmaceutical Reference Library
July 7, 2014

Thirty percent of approved drugs will be based on recombinant monoclonal antibody (rMab) drugs over the next 10 years. Glycosylation, the convalent addition of carbohydrates to proteins, can influence properties of rMab drugs and has to be closely monitored during drug development and production. Scientists from the University of California (California, USA) have developed a new liquid chromatography–mass spectrometry (LC–MS) N-glycan library based on eight commercially available recombinant monoclonal antibodies, for the rapid identification of glycosylated structures.

Teaching Old Drugs New Tricks
June 19, 2014

James Frahill, who is a Research Analyst at the Pfizer Process Development Centre (Cork, Republic of Ireland), spoke to Bethany Degg of The Column about the role of the chromatographer in the pharmaceutical process development group at Pfizer.

Profiling MDMA Impurities Using HS–SPME
June 19, 2014

Profiling impurities in MDMA (also known as ecstasy) is essential to forensic science as different profiles can provide clues about the source. Two researchers from Michigan State University (Michigan, USA) investigated the effect of liquid–liquid extraction (LLE), headspace solid-phase microextraction (HS–SPME), and different gas chromatography temperature programmes highlighting the need for standardized procedures.

DBS in Doping
June 19, 2014

Dried blood spot (DBS) sampling and high performance liquid chromatography coupled to high-resolution tandem mass spectrometry (HPLC–MS) has been demonstrated in the routine testing of athletes for anabolic steroid esters.


LCGC E-mail Newsletters
Global E-newsletters subscribe here:

Are you aware of CHROMacademy and the learning tools it offers?
Yes, I would like to know more
Yes, I am not interested
No, I would like to know more
No, I am not interested
Yes, I would like to know more
Yes, I am not interested
No, I would like to know more
No, I am not interested
View Results


Sample Prep Perspectives | Ronald E. Majors: Ron Majors, established authority on new column technologies, keeps readers up-to-date with new sample preparation trends in all branches of chromatography and reviews developments.
LATEST: UV Detector Problems

Perspectives in Modern HPLC | Michael W. Dong: Michael W. Dong is a senior scientist in Small Molecule Drug Discovery at Genentech in South San Francisco, California. He is responsible for new technologies, automation, and supporting late-stage research projects in small molecule analytical chemistry and QC of small molecule pharmaceutical sciences. LATEST: Superficially Porous Particles: Perspectives, Practices, and Trends

MS — The Practical Art | Kate Yu: Kate Yu brings her expertise in the field of mass spectrometry and hyphenated techniques to the pages of LCGC. In this column she examines the mass spectrometric side of coupled liquid and gas-phase systems. Troubleshooting-style articles provide readers with invaluable advice for getting the most from their mass spectrometers. LATEST: Radical Mass Spectrometry as a New Frontier for Bioanalysis

LC Troubleshooting | John Dolan: LC Troubleshooting sets about making HPLC methods easier to master. By covering the basics of liquid chromatography separations and instrumentation, John Dolan is able to highlight common problems and provide remedies for them. LATEST: Problems with Large-Molecule Separations

More LCGC Chromatography-Related Columnists>>

LCGC North America Editorial Advisory Board>>

LCGC Europe Editorial Advisory Board>>

LCGC Editorial Team Contacts>>

Click here