Articles by Bethany Degg - Chromatography Online
Articles by Bethany Degg

Bethany Degg

Assistant Editor

Detecting Microbial Compounds in Waterpipe Smoke
September 19, 2014

Waterpipes have been used to smoke tobacco and other substances for more than four centuries, and are widely believed to be less harmful than cigarettes. In a new study published in the journal Science of the Total Environment, gas chromatography coupled to mass spectrometry (GC–MS–MS) was performed to show that waterpipe smoke can contain potentially harmful microbial compounds.

Analysis of Breast Milk to Determine Agent Orange Exposure
September 19, 2014

Scientists in Vietnam have performed high-resolution gas chromatography coupled with high-resolution mass spectrometry (HRGC?HRMS) analysis of breast milk to determine the level of dioxin and furan exposure around the Da Nang Agent Orange hotspot in Vietnam. Agent Orange contamination is associated with elevated and persistent levels of dioxins and furans in the environment and are associated with the occurrence of birth defects among other side effects.

Improving MEKC–ESI–MS–MS Analysis of Synthetic Cathinones
September 19, 2014

A team of scientists based in the Czech Republic has developed a micellular electrokinetic chromatography method coupled with tandem mass spectrometry (MEKC–ESI–MS–MS) that uses salts of perfluorocarboylic acid as the volatile background electrolyte (BGE). The method was applied to the determination of 12 drugs from the class of synthetic cathinones in urine samples. According to the paper published in the Journal of Chromatography A, the BGE used to form micelles did not affect the electron ionization efficiency of MS. (1)

Chiral Separation of I-MAMP and d-MAMP in Saliva
September 11, 2014

Saliva is becoming ever more commonly used in drug testing over urine or blood samples because of its ease of collection. As such, existing testing methods are being adapted for application to accommodate a change in sample matrix. In a new study published in the Journal of Chromatography A, scientists from the National Institute on Drug Abuse (Maryland, USA) and the University of Maryland Baltimore (Maryland, USA) present the use of precolumn derivatization using N(?)-(2,4-dinitro-5-fluorophenyl)-l-alaninamide (Marfey?s reagent) prior to liquid chromatography–mass spectrometry (LC–MS) analysis for the quantitation of chiral amphetamines in plasma and saliva.1

Type 2 Diabetes Bioactive Compounds in Rosemary and Mexican Oregano
August 22, 2014

A new study published in the Journal of Agricultural and Food Chemistry highlights the potential use of rosemary and oregano in the management of Type 2 diabetes mellitus (T2DM).

Insight into Diet of Neanderthals by GC–MS Analysis of Faeces
August 22, 2014

Scientists from the Massachusetts Institute of Technology (MIT) in Massachusetts, USA, and University of La Laguna in Spain, have performed gas chromatography–mass spectrometry (GC?MS) analysis of Neanderthal faeces to demonstrate that Neanderthals could have eaten fruit and vegetables and were not necessarily dependent on a meat diet. According to the study published in the journal PLOS ONE, this is significant because it is thought that the specific diet of Neanderthals could have contributed towards the species extinction.

Analysis of House Dust to Determine Risk of Third-Hand Smoke Exposure
August 8, 2014

The risks associated with smoking tobacco and the potential effects of second-hand smoke are widely accepted by the medical community and have led to the introduction of smoking bans in public places in a number of different countries. Regardless of this, non-smokers are still at risk from tobacco smoke long after a cigarette has been extinguished. A new study in the journal Environmental International performed gas chromatography–mass spectrometry (GC–MS) to highlight the risk of potential third-hand smoke (THS) exposure.

Slower Py–GC–MS Unravels Cross-link Relationship in Amber
August 8, 2014

Amber is formed from plant resin that has polymerized and fossilized to form a resilient natural polymer. Jennifer Poulin and Kate Helwig, conservation scientists from the Canadian Conservation Institute in Ottawa, Canada, have developed a novel pyrolysis gas chromatography–mass spectrometry (py-GC–MS) method to characterize the structure of Class I amber that could be applied to other natural polymeric structures. Published in the journal Analytical Chemistry, the method demonstrates how a slower py-GC–MS technique can be performed to analyze natural polymers that contain cross-linked chemical moieties.

Applying Gas Chromatography to Environmental Geochemistry
July 24, 2014

In the first of a two-part Q&A The Column spoke to Paul A. Sutton, a research fellow in the Petroleum and Environmental Geochemistry Group (PEGG) at Plymouth University (Plymouth, UK), about the analysis of crude oil and how high temperature gas chromatography can be used to save millions of dollars for the oil industry.


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