Articles by Bethany Degg - Chromatography Online
Articles by Bethany Degg

Bethany Degg

Assistant Editor

Chiral Separation of I-MAMP and d-MAMP in Saliva
September 11, 2014

Saliva is becoming ever more commonly used in drug testing over urine or blood samples because of its ease of collection. As such, existing testing methods are being adapted for application to accommodate a change in sample matrix. In a new study published in the Journal of Chromatography A, scientists from the National Institute on Drug Abuse (Maryland, USA) and the University of Maryland Baltimore (Maryland, USA) present the use of precolumn derivatization using N(?)-(2,4-dinitro-5-fluorophenyl)-l-alaninamide (Marfey?s reagent) prior to liquid chromatography–mass spectrometry (LC–MS) analysis for the quantitation of chiral amphetamines in plasma and saliva.1

Insight into Diet of Neanderthals by GC–MS Analysis of Faeces
August 22, 2014

Scientists from the Massachusetts Institute of Technology (MIT) in Massachusetts, USA, and University of La Laguna in Spain, have performed gas chromatography–mass spectrometry (GC?MS) analysis of Neanderthal faeces to demonstrate that Neanderthals could have eaten fruit and vegetables and were not necessarily dependent on a meat diet. According to the study published in the journal PLOS ONE, this is significant because it is thought that the specific diet of Neanderthals could have contributed towards the species extinction.

Type 2 Diabetes Bioactive Compounds in Rosemary and Mexican Oregano
August 22, 2014

A new study published in the Journal of Agricultural and Food Chemistry highlights the potential use of rosemary and oregano in the management of Type 2 diabetes mellitus (T2DM).

Slower Py–GC–MS Unravels Cross-link Relationship in Amber
August 8, 2014

Amber is formed from plant resin that has polymerized and fossilized to form a resilient natural polymer. Jennifer Poulin and Kate Helwig, conservation scientists from the Canadian Conservation Institute in Ottawa, Canada, have developed a novel pyrolysis gas chromatography–mass spectrometry (py-GC–MS) method to characterize the structure of Class I amber that could be applied to other natural polymeric structures. Published in the journal Analytical Chemistry, the method demonstrates how a slower py-GC–MS technique can be performed to analyze natural polymers that contain cross-linked chemical moieties.

Analysis of House Dust to Determine Risk of Third-Hand Smoke Exposure
August 8, 2014

The risks associated with smoking tobacco and the potential effects of second-hand smoke are widely accepted by the medical community and have led to the introduction of smoking bans in public places in a number of different countries. Regardless of this, non-smokers are still at risk from tobacco smoke long after a cigarette has been extinguished. A new study in the journal Environmental International performed gas chromatography–mass spectrometry (GC–MS) to highlight the risk of potential third-hand smoke (THS) exposure.

Digital Microfluidics Coupled to Miniature MS
July 24, 2014

Great advances have been made in the field of miniaturization of mass spectrometers, opening up the potential to save time by performing analysis in the field; however, sample preparation has yet to catch up. A new study published in the journal Analytical Chemistry demonstrates the application of microfluidics integrated with a miniature mass spectrometer for the detection of illicit drugs in dried urine samples, which can simultaneously analyze four samples in under 15 min.

Antimicrobial Exposure of Expectant Mothers
July 24, 2014

Liquid chromatography–mass spectrometry (LC–MS) analysis has been performed on urine and cord blood samples from expectant mothers to explore the exposure to the antimicrobial agents triclosan (TCS) and tricarban (TCC). The agents have received increasing attention over recent years, with concerns being raised over lack of efficacy and potential toxicity to the environment, as well as human health.

Applying Gas Chromatography to Environmental Geochemistry
July 24, 2014

In the first of a two-part Q&A The Column spoke to Paul A. Sutton, a research fellow in the Petroleum and Environmental Geochemistry Group (PEGG) at Plymouth University (Plymouth, UK), about the analysis of crude oil and how high temperature gas chromatography can be used to save millions of dollars for the oil industry.

GC–MS Analysis of Blowflies to Detect Methamphetamine
July 24, 2014

Researchers from the University of Western Australia's Centre for Forensic Science have collaborated with the University of Turin's Department of Chemistry in Italy to develop a gas chromatography–mass spectrometry (GC–MS) method to analyze levels of methamphetamine (MA) in blowflies (Calliphora vomitoria L.).


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