LCGC North America, Jun 1, 2012

Column Watch Column

Stationary Phases for Modern Thin-Layer Chromatography

By Fred Rabel , Joseph Sherma

Advantages of the planar, off-line format of TLC relative to on-line column HPLC, the steps in TLC analyses, and future prospects of TLC are discussed.

LC Troubleshooting

When Should an Internal Standard be Used?

By John W. Dolan

Will an internal standard always improve data quality?

Column: MS-The Practical Art

New Frontiers for Mass Spectrometry in Lipidomics, Part II

By Kate Yu , Giuseppe Astarita

Mass spectrometry analysis of lipids in complex matrices is revolutionizing the way lipid research is conducted.

Innovations in HPLC

The Spectro-Electro Array: A Novel Platform for the Measurement of Secondary Metabolites in Botanicals, Supplements, and Beverages

By P.A. Ullucci , B.A. Bailey , D.H. Thomas , I.N. Acworth

HPLC with diode-array and electrochemical-array detection overcomes sensitivity and specificity limitations in natural products analysis.

The Essentials

Performance Characteristics Measured in Method Validation

Analytical method validation is the process of demonstrating that a method does what it is intended to do.

Articles

Capillary Electrophoresis–Mass Spectrometry for the Analysis of Biopharmaceuticals

By Rob Haselberg , Gerhardus J. de Jong , Govert W. Somsen

CE–MS using noncovalent coated capillaries provides advantages for purity and stability analysis of biopharmaceuticals.

Departments

Peaks of Interest

Agilent Announces Largest Acquisition in Its History

Market Profile

High-content screening (HCS) is a high-throughput method that enables the functional analysis of cells. HCS plays a vital role for drug discovery applications, including drug target verification and pathway detection, in both the pharmaceutical and biotechnology industries.

Product Resources

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If you are you planning to attend HPLC2013 Amsterdam what is your main reason?

	Column Watch \| Ronald E. Majors New Chromatography Columns and Accessories at Pittcon 2013, Part I
	Incognito \| Desert Island Data Systems
	MS: The Practical Art \| Kate Yu Nontargeted Metabolite Profiling by UHPLC-MS: A Case Study in Beer Reveals Effect of Temperature on Nonvolatile Small Molecules During Storage
	LC Troubleshooting \| John W. Dolan Gradient Elution, Part II: Equivalent Separations
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