By
Jennifer L. Simeone
,
Paul D. Rainville
,
Robert S. Plumb
The method development process required for the accurate quantification of both clopidogrel and its acid metabolite with a lower limit of quantification (LLOQ) of 1 pg/mL in human plasma is discussed.
This article describes how a food testing laboratory can transition routine high performance liquid chromatography (HPLC) methods to microflow LC for improved sensitivity, throughput, and robustness of analysis.
This article examines the various effects of phospholipids in liquid chromatography tandem mass spectrometry (LC–MS-MS) analysis and demonstrates a new phospholipid-removal approach.
A study of pharmaceuticals and personal care products in river water samples is presented from northeastern United States using ultrahigh-pressure liquid chromatography (UHPLC) coupled with TOF-MS for both targeted and nontargeted analytes