LCGC North America, Oct 1, 2004 - Chromatography Online
LCGC North America, Oct 1, 2004
Sample Prep Perspectives
Practical Tips on Preparing Plasma Samples for Drug Analysis Using SPME
By Fernando M. Lanças , Maria Eugênia C. Queiroz
This month'ss guest authors review the application of solid-phase SPME to the analysis of drugs in human plasma.
Gradient Performance Checks
By Jonathan J. Gilroy , John W. Dolan
Just how good are your gradients?
GC Connections
Finding a Needle in a Haystack
By John V. Hinshaw
This month's "GC Connections" examines the various ways – and their attendant benefits and drawbacks – with which chromatographers and chromatography data-handling systems locate and measure peaks
Directions in Discovery
Coupling Capillary Isoelectric Focusing with Mass Spectrometry
By Tim Wehr
This month'ss "Directions in Discovery" column discusses current work in the use of capillary isoelectric focusing and mass spectrometry as a multidimensional separation technique for proteomic studies.
Hydrophilic Interaction Chromatography Using Silica Columns for the Retention of Polar Analytes and Enhanced ESI-MS Sensitivity
By Eric S. Grumbach , Diane M. Wagrowski-Diehl , Pamela C. Iraneta , Bonnie Alden , Jeffrey R. Mazzeo
The use of a silica column for HILIC is examined, including mechanistic studies of analyte retention on silica in aqueous-organic mobile phases.
Validation and Implementation of In-Process Control HPLC Assays for Active Pharmaceutical Ingredients
By P.W. Wrezel , M.S. Hussain , I. Chion
The authors describe a sensible approach for validation and implementation of HPLC IPC assays.


LCGC E-mail Newsletters
Global E-newsletters subscribe here:

Are you aware of CHROMacademy and the learning tools it offers?
Yes, I would like to know more
Yes, I am not interested
No, I would like to know more
No, I am not interested
Yes, I would like to know more
Yes, I am not interested
No, I would like to know more
No, I am not interested
View Results


Sample Prep Perspectives | Ronald E. Majors:

LCGC Columnist Ron Majors, established authority on new column technologies, keeps readers up-to-date with new sample preparation trends in all branches of chromatography and reviews developments in existing technology lines.

LATEST: The Role of Selectivity in Extractions: A Case Study

History of Chromatography | Industry Veterans:

With each installment of this column, a different industry veteran covers an aspect of the evolution and continued development of the science of chromatography, from its birth to its eventual growth into the high-powered industry we see today.

LATEST: Georges Guiochon: Separation Science Innovator

MS — The Practical Art| Kate Yu:
Kate Yu is the editor of 'MS-The Practical Art' bringing her expertise in the field of mass spectrometry and hyphenated techniques to the pages of LCGC. In this column she examines the mass spectrometric side of coupled liquid and gas-phase systems. Troubleshooting-style articles provide readers with invaluable advice for getting the most from their mass spectrometers.

LATEST: Mass Spectrometry for Natural Products Research: Challenges, Pitfalls, and Opportunities

LC Troubleshooting | John Dolan:

LC Troubleshooting sets about making HPLC methods easier to master. By covering the basics of liquid chromatography separations and instrumentation, John Dolan, Vice President of LC Resources and world renowned expert on HPLC, is able to highlight common problems and provide remedies for them.

LATEST: LC Method Scaling, Part I: Isocratic Separations

More LCGC Chromatography-Related Columnists>>

LCGC North America Editorial Advisory Board>>

LCGC Europe Editorial Advisory Board>>

LCGC Editorial Team Contacts>>

Click here