LCGC North America, Oct 1, 2004 - Chromatography Online
LCGC North America, Oct 1, 2004
Sample Prep Perspectives
Practical Tips on Preparing Plasma Samples for Drug Analysis Using SPME
By Fernando M. Lanças , Maria Eugênia C. Queiroz
This month'ss guest authors review the application of solid-phase SPME to the analysis of drugs in human plasma.
3
Gradient Performance Checks
By Jonathan J. Gilroy , John W. Dolan
Just how good are your gradients?
GC Connections
Finding a Needle in a Haystack
By John V. Hinshaw
This month's "GC Connections" examines the various ways – and their attendant benefits and drawbacks – with which chromatographers and chromatography data-handling systems locate and measure peaks
Directions in Discovery
Coupling Capillary Isoelectric Focusing with Mass Spectrometry
By Tim Wehr
This month'ss "Directions in Discovery" column discusses current work in the use of capillary isoelectric focusing and mass spectrometry as a multidimensional separation technique for proteomic studies.
News
Hydrophilic Interaction Chromatography Using Silica Columns for the Retention of Polar Analytes and Enhanced ESI-MS Sensitivity
By Eric S. Grumbach , Diane M. Wagrowski-Diehl , Pamela C. Iraneta , Bonnie Alden , Jeffrey R. Mazzeo
The use of a silica column for HILIC is examined, including mechanistic studies of analyte retention on silica in aqueous-organic mobile phases.
Validation and Implementation of In-Process Control HPLC Assays for Active Pharmaceutical Ingredients
By P.W. Wrezel , M.S. Hussain , I. Chion
The authors describe a sensible approach for validation and implementation of HPLC IPC assays.
Products
Products
Literature
Literature

ADVERTISEMENT

LCGC E-mail Newsletters
Global E-newsletters subscribe here:




 
Survey
CHROMacademy
Are you aware of CHROMacademy and the learning tools it offers?
Yes, I would like to know more
Yes, I am not interested
No, I would like to know more
No, I am not interested
Yes, I would like to know more
69%
Yes, I am not interested
10%
No, I would like to know more
15%
No, I am not interested
6%
View Results

LCGC COLUMNISTS 2014

Column Watch: Ron Majors, established authority on new column technologies, keeps readers up-to-date with new sample preparation trends in all branches of chromatography and reviews developments. LATEST: When Bad Things Happen to Good Food: Applications of HPLC to Detect Food Adulteration


Perspectives in Modern HPLC: Michael W. Dong is a senior scientist in Small Molecule Drug Discovery at Genentech in South San Francisco, California. He is responsible for new technologies, automation, and supporting late-stage research projects in small molecule analytical chemistry and QC of small molecule pharmaceutical sciences. LATEST: HPLC for Characterization and Quality Control of Therapeutic Monoclonal Antibodies


MS — The Practical Art: Kate Yu brings her expertise in the field of mass spectrometry and hyphenated techniques to the pages of LCGC. In this column she examines the mass spectrometric side of coupled liquid and gas-phase systems. Troubleshooting-style articles provide readers with invaluable advice for getting the most from their mass spectrometers. LATEST: Radical Mass Spectrometry as a New Frontier for Bioanalysis


LC Troubleshooting: LC Troubleshooting sets about making HPLC methods easier to master. By covering the basics of liquid chromatography separations and instrumentation, John Dolan is able to highlight common problems and provide remedies for them. LATEST: How Much Can I Inject? Part I: Injecting in Mobile Phase


More LCGC Columnists>>

LCGC North America Editorial Advisory Board>>

LCGC Europe Editorial Advisory Board>>

LCGC Editorial Team Contacts>>


Click here