Liquid Chromatography (LC/HPLC)

Mar 01, 2016
LCGC North America
How suitable is the column plate number for system suitability testing?
Feb 01, 2016
LCGC North America
Pavel Jandera discusses building his own LC instrument, the birth of modern HPLC, the importance of exploring (and understanding) earlier research papers, and current trends in contemporary chromatography. He also offers inspiring advice for young chromatographers.
Feb 01, 2016
LCGC North America
This exploration of the fundamental interactions involved in PFP stationary phases will facilitate the choice of appropriate stationary phases and help analysts develop more robust and reliable methods.
Feb 01, 2016
LCGC North America
The silica-based packing in reversed-phase columns is not inert. Here we consider what happens when the mobile phase pH is too high or too low.
Jan 01, 2016
LCGC North America
By LCGC Editors
Affinity separations offer great potential for pharmaceutical analysis.
Jan 01, 2016
LCGC North America
An investigation into the root cause of new peaks revealed an unusual source of contamination.
Jan 01, 2016
LCGC North America
Best practices and recent advances in characterizing glycosylation
Nov 01, 2015
Special Issues
This article provided guidance for working with the low-dispersion, small-volume columns that were gaining popularity in 2003. These considerations are still appropriate today with the short, narrow HPLC and UHPLC columns now in vogue. Anatomy
Nov 01, 2015
LCGC North America
Some new approaches can provide superior protein separations. These include using columns of highly efficient superficially porous silica particles and techniques involving MS-friendly mobile phases with effective methods for changing protein selectivity (band spacings) by column type and organic mobile-phase modifiers.
Nov 01, 2015
LCGC North America
So you think you know all about UV detection? Check your knowledge against this article on the principles and key variables of ultraviolet detection.
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