Liquid Chromatography (LC/HPLC)

Nov 01, 2015
LCGC North America
The column is at the core of chromatography, and the past 25 years have seen continuous improvements in HPLC and UHPLC columns. Here, Majors assesses the most important developments, looking at how we got this far and where we may be heading.
Oct 02, 2015
Special Issues
The use of off-line 2D-LC–MS for the characterization of HCPs and their monitoring during downstream processing.
Oct 02, 2015
Special Issues
The technical requirements for a successful LC–MS–MS method for the quantitation of biopharmaceuticals are presented and the advantages and disadvantages compared to ligand-binding assays are evaluated.
Oct 01, 2015
LCGC North America
Miniaturized separation techniques are advantageous for the analysis of illicit drugs and new psychoactive substances.
Oct 01, 2015
LCGC Europe
Solvent costs too high? Here are some ideas on how to decrease the amount of mobile phase you use.
Oct 01, 2015
LCGC Europe
This current paper provides useful tips for smooth validation of multi‑analyte LC–MS–MS methods and summarizes important validation outcomes for 295 analytes, including over 200 mycotoxins.
Sep 01, 2015
LCGC Europe
HPLC 2015, chaired by Gérard Hopfgartner was held in Geneva, Switzerland, from 21–25 June. This review covers some of the highlights of the symposium including stationary phase developments, particle technology, and growing application areas for HPLC.
Sep 01, 2015
LCGC Europe
The authors present a method for comparing the levels of baseline interference arising from common laboratory mobile phase contamination sources and assess different approaches for removing dissolved contaminants to generate interference free chromatogram baselines. This article demonstrates that recirculating mobile phase through a semi-preparative scale column using a reagent delivery pump to be more effective than previously published mobile phase decontamination methods.
Sep 01, 2015
LCGC North America
Highlights from the symposium, including particle technology, stationary-phase developments, and growing application areas, as well as the trends and future perspectives we culled from the conference.
Aug 10, 2015
The Column
Automated high-throughput dynamic light scattering (HT–DLS) can enable rapid and unattended assessment of sample purity in biopharmaceutical samples, maximizing the reliability and productivity of the candidate selection process. This article explains more.
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