Today’s plenary is an award lecture by Richard M. Caprioli of Vanderbilt University. Caprioli is the recipient of the 2014 ASMS Award for a Distinguished Contribution in Mass Spectrometry for the development of matrix-assisted laser desorption ionization (MALDI) imaging mass spectrometry and its application to molecular mapping of tissues in biology and medicine. His award lecture today will be held in Exhibit Hall AB, at 4:45 pm.
In MALDI imaging mass spectrometry, molecular measurements can be made directly from tissues, adding significantly to the information that can be obtained from these specimens. Caprioli’s work on this technique has made significant contributions to the study of proteins, lipids, metabolites, and pharmaceutical compounds. Since the publication of his seminal 1997 paper (1) showing the power of MALDI imaging mass spectrometry for tissue analysis, Caprioli has pioneered advancements in sample preparation, instrumentation, and informatics approaches that have considerably advanced the technology and made it accessible to hundreds of laboratories worldwide.
The impact of his work is evident in the numerous commercial platforms that use this technology. Approximately 2,500 papers have been published to date on the subject of MALDI imaging mass spectrometry.
Caprioli is the Stanford Moore Chair in Biochemistry and Director of the Mass Spectrometry Research Center at Vanderbilt University.
(1) Anal. Chem. 69(23), 4751-4760 (1997).