Special Issues April 2016

April 2016 | Volume 34, Issue 4
Introduction
A brief introduction to the articles presented in this supplement
Articles
This fit-for-purpose LC–MS-based method provides fast analysis of four mycotoxins using standard HPLC equipment with a pentafluorophenyl SPP column.
An investigation of C18 and phenyl-hexyl column chemistries for definitive identification of 13 synthetic cannabinoid metabolites in patient samples.
When presented with a new analyte, a bioanalytical CRO must quickly develop a robust method with good chromatographic resolution, repeatable results, and a quick run time. Recent developments in LC column technology make that possible.
Recent advances in chiral stationary phases have enabled higher efficiency and faster separations in studies of the differing enantiomeric activity of pesticides, their environmental transformation, and the degradation of pollutants in general.
When selecting the optimum phase for SEC separations, several key column parameters must be considered carefully.
As clinical diagnostic assays move to LC–MS-MS, the emphasis has turned to emerging stationary phases that use alternative mechanisms of retention to separate the analyte–interference critical pairs.
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