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Researchers at Oregon State University and Dow Neurobiology developed a standardized aroma lexicon for characterizing the aromatic attributes of Cannabis inflorescence with an associated sensory method that included the use of gas chromatography in data analysis.

LCGC International and the HTC-19 Scientific Committee celebrate innovation in separation science with the 2026 HTC Innovation Award. Previous winners include Bob Pirok, Szabolcs Fekete, Ryan Kelly and Caroline Huhn.

Researchers at the University of Buffalo used combined middle-up and bottom-up LC–MS/MS to characterize the HIV-1 broadly neutralizing antibody PGT 121. They identified multiple Fc and site-specific glycoforms and an unexpected N-terminal serine, revealing significant structural heterogeneity. This integrated approach enhances understanding of bNAb structure, supporting quality control and clinical development. LCGC International spoke to Troy Wood, corresponding author of the paper resulting from this research.

Discover how women in chromatography are breaking barriers, fostering community, and inspiring the next generation in STEM through mentorship and courage.

Explore the complexities of GLP-1 impurity detection using HPLC/UHPLC and innovative strategies to enhance analysis and regulatory compliance.

Researchers focused on the early stages of developing innovative plant-based active ingredients for skincare, using HPLC to determine which species should be shortlisted for phytochemical profiling.

Giulia Mazzoccanti spoke to LCGC International about the development and application of electrostatic repulsion-reversed phase (ERRP) chromatography for peptide separations.

Metabolomic profiling and the identification of metabolomic markers following HPAI H5N1 infection in chicken was performed in an Indian research study, with metabolite extracts analyzed using LC-MS/MS.

Discover innovative LC–HRMS methods for analyzing RNA-based therapeutics, enhancing biopharma development and regulatory compliance in drug characterization.

Static and dynamic electrostatic repulsion-reversed phase (ERRP) has been compared for the separation of peptide impurities.

Researchers evaluated the antidiabetic potential of peanut oil, known for its high phytochemical content and medicinal properties, using GC-MS to collect and classify fatty acid compounds within the oil.

This episode of Behind the Peaks focuses on the importance of sound statistical practices in chromatographic analysis.