Analysis of PFOA and PFOS in Water Using Reversed-Phase HPLC with Suppressed Conductivity Detection
Suppressed conductivity detection is a well-developed method for detecting charged species. Reversed-phase high-performance liquid chromatography (RP-HPLC) is a well developed method of separating substances on the basis of hydrophobicity. There are some situations where it is advantageous to use these two methods together. Perfluoro-acids (PFOAs) are one class of compounds that are ionic, hydrophobic and have low UV absorbance and are, therefore, suited to this combination.