In his final column before retirement, John Dolan reminisces about his years as the author of “LC Troubleshooting”, and some of the changes that have taken place in liquid chromatography (LC) technology during that time.
How do non-alkylsilica columns provide us an additional dimension of column selectivity?
How do non-alkylsilica columns provide us an additional dimension of column selectivity?
When developing or modifying an LC separation, a common strategy is to change selectivity by choosing a new column. Here’s guidance for making that selection.