Michael Lämmerhofer | Authors

Michael Lämmerhofer is a full professor (W3) for pharmaceutical (bio-)analysis at the University of Tübingen, Germany. His research interests include the development of functionalized separation materials (chiral stationary phases, mixed‑mode phases, chemo- and bioaffinity materials, nanoparticles, monoliths), metabolomics and lipidomics, pharmaceutical analysis (impurity profiling, enantioselective analytics), multidimensional separations, and biopharmaceuticals analysis.


Evaluation of Kinetic Performance of Reversed-Phase Columns for Protein Separations by Gradient Kinetic Plots

This article compares the performance of wide-pore silica monolithic, sub-2µm FPP, and SPP columns, addresses the question of whether 1000 Å or 400 Å SPP columns are more suitable for reversed-phase LC-type protein separations, and presents a kinetic performance comparison of different columns.

Trends in Enantioselective High Performance Liquid Chromatography

Enantioselective high performance liquid chromatography (HPLC) is slowly adopting the modern particle technologies (sub-2-µm fully porous particles [FPPs] and sub-3-µm superficially porous silica particles [SPPs]) that have been well known in reversed-phase LC for the past decade. The most significant benefit is that enantiomer separations can be performed much faster, which is of interest in high-throughput screening applications and multidimensional enantioselective HPLC analysis. The state of the art is briefly discussed with some examples documenting the potential of core–shell particle technology and comprehensive multidimensional separations.

ISC 2014: The Sound of Chromatography

The hills will be alive with the sound of chromatography when the 30th International Symposium on Chromatography (ISC 2014) takes place from 14?18 September 2014 in Salzburg, Austria.

Enantiomer and Topoisomer Separation of Acidic Compounds on Anion-Exchanger Chiral Stationary Phases by HPLC and SFC

Quinine- and quinidine-derived anion-exchanger chiral stationary phases have proven to be versatile in enantiomer separation of acidic compounds in HPLC. In this article, the authors demonstrate their performance in specific HPLC applications involving enantiomer resolution and topoisomer separation.