Michael W. Dong | Authors


“Practical HPLC Simulator”: A Useful Freeware for Learning HPLC

The “practical HPLC simulator” is a freeware program that uses actual separation data to demonstrate the chromatographic principles under isocratic or gradient conditions and the impacts of instrumental, column, and mobile phase parameters on method performance.

Bioanalysis of Small-Molecule Drugs and Metabolites in Physiological Samples by LC–MS, Part 1: Overview

This article is the first of four on the bioanalysis of small-molecule drugs and metabolites by liquid chromatography–mass spectrometry (LC–MS). In this article, we provide an overview of the fundamentals, workflow, regulations, and modern trends on these quantitative assays.