Mirlinda Biba | Authors

Analysis and Preparative Separations Group, Process Research Department, Merck & Co., Inc., Rahway, NJ.


Evaluation of Achiral Stationary Phases for Gradient Screening with Supercritical Fluid Chromatography

Unlike reversed-phase liquid chromatography, SFC lacks a universal stationary phase. Thus, it is important to re-evaluate the default column screening library used with SFC. In this study, three uncommon achiral SFC columns were investigated and compared to three popular stationary phases.