OR WAIT 15 SECS
© 2020 MJH Life Sciences and Chromatography Online. All rights reserved.
© 2020 MJH Life Sciences™ and Chromatography Online. All rights reserved.
University of Pierre et Marie Curie, Paris, France.
Size exclusion chromatography (SEC) coupled to light-scattering, viscometer and refractive index detectors is a common technique used for the characterization of polymers. In this article the solution conformations of two chimeric IgG3 antibodies were studied using this coupled triple detection technique. Conclusions indicate that the results allow hydrodynamic modeling of the antibody structures.