Valerie Pichon | Authors


Different Approaches to Synthesizing Molecularly Imprinted Polymers for Solid-Phase Extraction

Molecularly imprinted polymers (MIPs) are synthetic polymeric materials that mimic immunosorbents. They are widely used as sorbents for solid-phase extraction (SPE). The most common way to synthesize them is bulk polymerization because of its simplicity and versatility. This produces a hard monolith that has to be ground and sieved to obtain particles in the desired size range. However, the partial loss of the materials as fine dusts; the irregular shape of the particles produced and their wide size distribution, have led to a search for different polymerization methods to offset the drawbacks of the bulk polymerization process.

Molecularly Imprinted Polymers: Developments and Applications of New Selective Solid-Phase Extraction Materials

MIPs are synthetic polymeric materials possessing specific cavities designed for a target molecule. The various parameters affecting extraction selectivity are discussed in the article and the potential of MIPs as selective sorbents reviewed.