Hot Topics in Mass Spectrometry | Special Issues

LCGC E-Books

Mass Spectrometry Support to Mitigate Product Recall Situations in the Pharmaceutical Industry

October 01, 2021

39

s10

These case studies illustrate how the pharmaceutical industry utilizes mass spectrometry–based solutions to address product quality concerns, particularly when extremely low detection limits are required and when development resources are limited.

Mass Spectrometry–Based Process Analytical Technologies for Cell Therapies

October 01, 2021

39

s10

Even compared to other biopharmaceuticals, chimeric antigen receptor (CAR) T-cell therapies are particularly complex. Mass spectrometry (MS)–based process analytical technologies can be a powerful tool in identifying and monitoring key attributes throughout the manufacturing process.

New Aspects in the Integration of Mass Spectrometry Technologies in the Biopharmaceutical Industry

October 01, 2021

39

s10

Recent developments in high-resolution mass spectrometry (HRMS) are aiding biopharmaceutical development and simplifying routine monitoring, with applications in areas like multi-attribute methods, coupling established purity methods with MS, and subunit analysis.