Special Issues-06-01-2015

Special Issues

Vol 28 No s6 LCGC Europe June 2015 Recent Developments in HPLC and UHPLC Supplement PDF

June 02, 2015

Issue PDF

0

Click the title above to open the LCGC Europe June 2015 Recent Developments in HPLC and UHPLC Supplement, Vol 28, No s6, in an interactive PDF format.

Recent Developments in HPLC and UHPLC

June 01, 2015

Articles

0

Introduction from the Guest Editor.

Precision of Internal Standard and External Standard Methods in High Performance Liquid Chromatography

June 01, 2015

Articles

0

Internal standard methods are used to improve the precision and accuracy of results where volume errors are difficult to predict and control. A systematic approach has been used to compare internal and external standard methods in high performance liquid chromatography (HPLC). The precision was determined at several different injection volumes for HPLC and ultrahigh‑pressure liquid chromatography (UHPLC), with two analyte and internal standard combinations. Precision using three methods of adding the internal standard to the analyte before final dilution was examined. The internal standard method outperformed external standard methods in all instances.