Biopharmaceutical Analysis: The State Of The Art – A Virtual Symposium

This event is now available on-demand!


Event Overview:

The biopharmaceutical sector plays a pivotal role in the society and separation scientists are at the heart of developing innovative therapeutics.
In the first session leading separation scientists will explain how they apply theory and the latest advances in technology to solve very difficult challenges in this exclusive virtual symposium moderated by two emerging leaders from LCGC Europe’s Rising Stars of Separation Science Series: Jelle de Vos, RIC, Belgium and Valentina D’Atri, University of Geneva, Switzerland.
The second session of informative sessions will involve presentations from  leading manufacturers in biopharmaceutical analysis, illustrating how their technologies solve problems and achieve results in practice.


Key Learning Objectives:
  • Find out about the latest cutting-edge advances in biopharmaceutical analysis
  • Learn how multi-column processing continuous processing can enhance the production of peptides
  • An update on recent advances in monoclonal antibody-,peptide-, and oligonucleotide analysis
  • The benefits that HILIC–MS and SAX-HPLC–MS offer the analyst
  • The evolving role of glycomics in this exciting sector
  • Vaccine research… and more!
Who Should Attend:

Laboratory scientists and researchers involved in cutting-edge research in the biopharmaceutical sector using separation science who want to learn about the latest research advances in this vibrant area of analytical chemistry and how the latest technologies work in “real word” situations.


For any technical questions please contact Jorge De La Banderas: jdelabanderas@mjhlifesciences.com



Symposium Agenda:
Symposium Agenda:
Day 1: Monday, November 21st, 2022 at 1:00pm – 2:55pm GMT


1:00pm GMT        Opening Remarks from our Moderator and Co-Chair, Valentina D'Atri
Valentina D'Atri; Teaching Fellow; Department of the School of Pharmaceutical Sciences of the University of Geneva, Switzerland


1:15pm GMT        Using Protein-specific Retention Behavior to Improve the Characterization of Therapeutic Antibodies
Bastian L. Duivelshof; PhD Student; Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), School of Pharmaceutical Sciences, University of Geneva, Geneva Switzerland.

 
1:35 pm GMT        Boosting the Downstream Processing of Therapeutic Peptides by Means of Multicolumn Continuous Chromatography
Martina Catani; Assistant Professor; Department of Chemical, Pharmaceutical and Agricultural Sciences – DOCPAS; University of Ferrara, Ferrara (ITALY)



1:55pm GMT        Development of Innovative Analytical Approaches for the Separation of Large RNA Oligonucleotide Impurities and their Sequencing
Alexandre Goyon, PhD; Small Molecule Pharmaceutical Sciences (SMPS), Genentech


2:15pm GMT        Multi-attribute Monitoring of CQAs for Recombinant Monoclonal Antibodies
Anurag S. Rathore; Chair Professor; Coordinator, DBT COE for Biopharmaceutical Technology. Professor, Department of Chemical Engineering, Indian Institute of Technology, Delhi Hauz Khas, 110016 New Delhi (INDIA)




2:35pm GMT        Question and Answer Session


2:55pm GMT        COFFEE BREAK

Session 2: Talks From Our Sponsors

3:30pm GMT        Expert Advice on Biologics Sample Prep
Geoffrey Rule, Ph.D. ; Principal Scientist, Merck ; Mark Pawlicki, Global Product Manager, Merck, Felicia Riordan, Senior Analytical Research Scientist, Merck; 

                              Expert Advice on Developing LC-MS Methods for Biomolecule Analysis
Cory Muraco, Biomolecule Workflows Product Manager; Merck; Felicia Riordan, Senior Analytical Research Scientist, Merck; Hillel Brandes, Analytical Specialist, Merck
                                
                                
4:00pm GMT        Guideline for Modern Oligonucleotide RP-(U)HPLC Separations
Dr. Kevin Brahm; Key Account Manager International, YMC Europe GmbH

4:30pm GMT        Light scattering of biomolecules – theory and applications
Moritz Susewind, PhD; Senior researcher GPC software department, PSS GmbH, Now part of Agilent

5:00pm GMT       Getting the Best out of Solid Core Technology for Large Molecule Analysis
Tony Edge; R&D Leader and Scientific Advisor, Avantor

Day 2: Tuesday, November 22nd, 2022 at 1:00pm – 3:15pm GMT

1:00pm GMT        Opening Remarks from Co-Chair Jelle De Vos
Jelle De Vos; Senior Scientist; Research Institute for Chromatography (RIC), Belgium


1:15pm GMT        SAX-HPLC-MS Unravels the Heterogeneity of Myozyme® Glycosylation at Intact Glycoform Level
Fiammetta Di Marco; PhD Student; Department of Biosciences and Medical Biology, Bioanalytical Research Labs, University of Salzburg, Austria

1:35pm GMT        HILIC-MS Separation of Intact Glycoproteoforms. How Capillary Columns and Acrylamide-based Materials Can Help in the Analysis of Low Abundance Species
Andrea Gargano; Assistant Professor; Division of BioAnalytical Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
 
1:55pm GMT        Glycoconjugated Vaccines: Analytical Issues and Latest Developments
Caterina Temporini; Associate Professor; Department of Drug Sciences, University of Pavia, Via Taramelli 12, 27100 Pavia (ITALY)

 
2:15pm GMT       Bridging structure and function of biotherapeutics by emerging chromatographic technologies
Bingchuan Wei, PhD; Early Research and Development, Genentech


2:35pm GMT        Analytical Methods for Oligonucleotide Therapeutics
Claus Rentel, PhD; Ionis Pharmaceuticals

2:55pm GMT        Question and Answer Session

3:15pm GMT        COFFEE BREAK

Session 2 - Talks From Our Sponsors 

3:30pm GMT        AI driven labs – the revolution has begun!
Mark Moorman; VP AA/AI, LabVantage Solutions

4:00pm GMT        On-Column Digest Followed By SPE Desalting For Rapid And Simplified Sample Processing without Sample Transfer
Dr. John D Laycock; Director of Technology and Product Development, Tecan US

4:30pm GMT        How Multi-Angle Light-Scattering (MALS) Detection Complements Biomolecule Analysis
Andrea Krumm; Product Manager Analytical Columns EMEA, Tosoh Bioscience


Today's Featured Speakers:
Dr. Valentina D’Atri
Research and Teaching Fellow
Department of Analytical Sciences, School of Pharmaceutical Sciences, University of Geneva, Switzerland
Dr. Jelle De Vos
Dr. Jelle De Vos
Senior Scientist
Research Institute for Chromatography (RIC), Belgium
Bastiaan L. Duivelshof
Bastiaan L. Duivelshof
PhD Student
Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), School of Pharmaceutical Sciences, University of Geneva, CMU rue Michel-Servet 1, 1211 Geneva (SWITZERLAND)
Martina Catani
Martina Catani
Assistant Professor
Department of Chemical, Pharmaceutical and Agricultural Sciences – DOCPAS; University of Ferrara, via L. Borsari 46, 44121 Ferrara (ITALY)
Alexandre Goyon
Alexandre Goyon
PhD
Small Molecule Pharmaceutical Sciences (SMPS), Genentech
Anurag S. Rathore
Anurag S. Rathore
Chair Professor
Coordinator, DBT COE for Biopharmaceutical Technology. Professor, Department of Chemical Engineering, Indian Institute of Technology, Delhi Hauz Khas, 110016 New Delhi (INDIA)
Fiammetta Di Marco
Fiammetta Di Marco
PhD Student
Department of Biosciences and Medical Biology, Bioanalytical Research Labs, University of Salzburg, Hellbrunner Straße 34, 5020 Salzburg (AUSTRIA)
Andrea Gargano
Andrea Gargano
Assistant Professor
Division of BioAnalytical Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, de Boelelaan 1085, 1081 HV Amsterdam (THE NETHERLANDS)
Caterina Temporini
Caterina Temporini
Associate Professor
Department of Drug Sciences, University of Pavia, Via Taramelli 12, 27100 Pavia (ITALY)
Bingchuan Wei
Bingchuan Wei
PhD
Early Research and Development, Genentech
Claus Rentel
Claus Rentel
PhD
Ionis Pharmaceuticals