This study demonstrates the performance of thermal desorption (TD) analysis for the monitoring of 'air toxic' compounds according to US EPA Method TO-17. The results show excellent precision, linearity, and low method detection limits for all 65 target compounds across a wide volatility range. Key capabilities highlighted include the ability to re-collect and re-analyse split samples, as well as determining safe sampling volumes through breakthrough testing. The application of TD-GC-MS for trace-level air toxics analysis is shown to be a robust and reliable technique, meeting the stringent requirements of the US EPA method.
LC/MS Based Characterization Workflow of GLP-1 Therapeutic Peptide Liraglutide and Its Impurities
January 14th 2025This application note demonstrates a liquid chromatography/quadrupole time-of-flight mass spectrometer (LC/Q-TOF MS) workflow for the identification and characterization of therapeutic peptides.