Elevating pH to Improve a Drugs of Abuse Separation

News
Article

Sponsored Content

Using HALO®Elevate C18 and a high pH mobile phase obtains a great separation of drugs of abuse and metabolites without the use of a specialized stationary phase.

Related Content
Site Logo

REVOLUTIONIZE YOUR LAB WORK: Introducing the Compact and Portable Autosampler for the Axcend Focus LC®

Axcend
January 16th 2025
Article

Site Logo

GC and GC/MS Frequently Asked Questions

Agilent Technologies, Inc.
January 15th 2025
Article
Site Logo

Robust Column Performance for Wide Pore Size Exclusion Columns for Adeno-Associated Virus Particles (AAVs) Analysis

Agilent Technologies, Inc.
January 14th 2025
Article

This application note demonstrates the superior resolution and recovery of Agilent AdvanceBio SEC 500 Å columns when compared with competitor products for AAVs.

Site Logo

Analysis of Oligonucleotides Using an Ion-Pairing-Free Reversed-Phase Method with TOF LC/MS

Agilent Technologies, Inc.
January 14th 2025
Article

This app note describes a non ion-pairing reversed-phase LC/MS method for highly modified ASOs, DNA, sgRNA, and siRNA ranging from 14- to 103-mer oligonucleotides.

Site Logo

LC/MS Based Characterization Workflow of GLP-1 Therapeutic Peptide Liraglutide and Its Impurities

Agilent Technologies, Inc.
January 14th 2025
Article

This application note demonstrates a liquid chromatography/quadrupole time-of-flight mass spectrometer (LC/Q-TOF MS) workflow for the identification and characterization of therapeutic peptides.

Site Logo

Batch Reproducibility and Effect of Gradient Delay Volume on Impurity Separations of Chlorhexidine Digluconate

Phenomenex, Inc.
January 13th 2025
Article

An optimized liquid chromatography (LC) method offers improved impurity separation, no batch reproducibility issues, and is unaffected by changes in gradient delay volume settings.