The G protein-coupled receptors (GPCR) are found throughout the entire body and have shown significance in the development of new therapeutic treatments. Isolation of seven classic GRPC peptides initiating in the GI tract highlights the benefits of using the polymer-based PRP-3, a reversed-phase resin. The covalent bonds found in the PRP-3 exhibit advantageous interactions between the biological π bonds found in the peptides and the available aromatic benzyl rings of the resin.
Progress with Alternative Solvents for SIFT-MS: 2024 Update
January 30th 2025Explore advancements in utilizing alternative solvents for SIFT-MS. This tech note introduces three new solvents—acetonitrile, N,N'-dimethylpropyleneurea (DMPU), and propylene glycol (PG)—and highlights the enhanced sensitivity and applications of existing solvents like triacetin. The findings demonstrate significant benefits in analyzing diverse VOCs while addressing challenges in method development.