This morning session, beginning at 8:30 am, honors Luis Colón of the University at Buffalo, the 2023 winner of the Dal Nogare Award. Presented annually by the Chromatography Forum of the Delaware Valley (CFDV), this award recognizes outstanding scientists who have made great contributions to understanding the chromatographic process. Mary Ellen McNally of FMC will present the award and preside over the session, which will be held in Room 123.
At 8:40 am, Colón will present his study of a diarylethene (DAE) photochromic compound by high-pressure liquid chromatography (HPLC) and/or supercritical fluid chromatography (SFC). For this experiment, Colón and his team studied the formation of a DAE ring-closed isomer via HPLC and SFC. This presentation will show the details of the chromatographic experimental conditions and the findings related to the formation of different DAE isomeric species.
At 9:15 am, Apryll Stalcup of Dublin City University will share tales of her career journey in separation science, in which many blind alleys turned into golden opportunities and new research pathways, in both the United States and Europe.
At 9:50 am, Robert Kennedy of the University of Michigan will present his laboratory’s most recent efforts to push the limits of liquid chromatography (LC) in terms of speed and efficiency. By testing new sample introduction approaches and creating new high-pressure systems, they have been reaching higher efficiencies and improving compound detection in complex mixtures.
At 10:40 am, Susan Olesik of The Ohio State University will share her latest work to improve LC and mass spectrometry (MS) using enhanced-fluidity liquid solvents. Adding carbon dioxide to conventional liquid mobile phases enhances diffusion, decreases viscosity, and maintains mixture polarity, all of which reduces the necessary time needed for analysis. These presented results will illustrate the value of enhanced fluidity liquid mobile phases separations using these retention mechanisms and show the value of these solvents for enhancing mass spectrometric analyses.
At 11:15 am, Stephen Weber of the University of Pittsburgh will discuss the use of electroosmotic perfusion for sampling in the brain. Weber’s laboratory made the discovery that small electrical currents could be used to direct fluid through brain tissue over short distances between a source and a sink, the latter leading to collection or directly to a measurement apparatus. Their most recent work applies two-photon polymerization using a commercial instrument (Nanoscribe) to create devices for passing peptide substrate through tissue in vivo, collecting products, and measuring.
The session will conclude at 11:50 am.