Column: Perspectives in Modern HPLC

Aug 01, 2017
LCGC North America
UHPLC’s benefits include fast analysis, high-resolution separations, reduced solvent and sample usage, enhanced sensitivity and precision, and more.
Jun 01, 2017
LCGC North America
In this three-part series, we assess how UHPLC evolved into a modern platform. We start by examining the most important features common to most commercial instruments.
Apr 01, 2017
LCGC North America
A review of the new high performance liquid chromatography (HPLC) instruments, modules, and software that were introduced at Pittcon 2017 and during the year prior, including descriptions of their innovative features and significant benefits.
Oct 01, 2016
LCGC North America
Simpler methodologies should be considered for the quantitative determination of counterions associated with pharmaceutical salts.
Aug 01, 2016
LCGC North America
How one organization encouraged its staff to develop HPLC methods using fewer column brands and dimensions to reduce waste
Jun 01, 2016
LCGC North America
This universal method is fast (2 min) and provides reasonable peak capacity and excellent peak shapes for many new chemical entities.
Apr 01, 2016
LCGC North America
Our annual review of new HPLC instruments and related products highlights the innovative features of new HPLC systems, modules, software, and product extensions.
Dec 01, 2015
LCGC North America
An overview of modern practices of quality control in small-molecule drug development
Oct 01, 2015
LCGC North America
An overview of modern practices of separation science in smallmolecule drug development and highlights on approaches in HPLC method development.
Aug 01, 2015
LCGC North America
This installment provides an overview of high-throughput characterization techniques of drug leads to support small molecule drug discovery programs in a pharmaceutical company. A myriad of analytical chemistry techniques including separation science methodologies are used to confirm the structures and identities, quantitating the concentrations of stock solutions, and measuring key physicochemical properties of the new chemical entities (NCE). A case study is used here to illustrate the details of these applications in high-throughput characterization.
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